Nanotopography-guided tissue engineering and regenerative medicine
Human tissues are intricate ensembles of multiple cell types embedded in complex and well-
defined structures of the extracellular matrix (ECM). The organization of ECM is frequently …
defined structures of the extracellular matrix (ECM). The organization of ECM is frequently …
Biomimetic tissues on a chip for drug discovery
AM Ghaemmaghami, MJ Hancock, H Harrington… - Drug discovery today, 2012 - Elsevier
Developing biologically relevant models of human tissues and organs is an important
enabling step for disease modeling and drug discovery. Recent advances in tissue …
enabling step for disease modeling and drug discovery. Recent advances in tissue …
Directed 3D cell alignment and elongation in microengineered hydrogels
Organized cellular alignment is critical to controlling tissue microarchitecture and biological
function. Although a multitude of techniques have been described to control cellular …
function. Although a multitude of techniques have been described to control cellular …
Electrically conductive nanofibers with highly oriented structures and their potential application in skeletal muscle tissue engineering
MC Chen, YC Sun, YH Chen - Acta biomaterialia, 2013 - Elsevier
Recent trends in scaffold design have focused on materials that can provide appropriate
guidance cues for particular cell types to modulate cell behavior. In this study highly aligned …
guidance cues for particular cell types to modulate cell behavior. In this study highly aligned …
Skeletal muscle tissue engineering: methods to form skeletal myotubes and their applications
Skeletal muscle tissue engineering (SMTE) aims to repair or regenerate defective skeletal
muscle tissue lost by traumatic injury, tumor ablation, or muscular disease. However, two …
muscle tissue lost by traumatic injury, tumor ablation, or muscular disease. However, two …
Insight into muscle stem cell regeneration and mechanobiology
Stem cells possess the unique ability to differentiate into specialized cell types. These
specialized cell types can be used for regenerative medicine purposes such as cell therapy …
specialized cell types can be used for regenerative medicine purposes such as cell therapy …
Patterning the differentiation of C2C12 skeletal myoblasts
Mammalian cells are sensitive to the physical properties of their micro-environment such as
the stiffness and geometry of the substrate. It is known that the stiffness of the substrate plays …
the stiffness and geometry of the substrate. It is known that the stiffness of the substrate plays …
Bioprinting of growth factors onto aligned sub-micron fibrous scaffolds for simultaneous control of cell differentiation and alignment
The capability to spatially control stem cell orientation and differentiation simultaneously
using a combination of geometric cues that mimic structural aspects of native extracellular …
using a combination of geometric cues that mimic structural aspects of native extracellular …
Micropatterned conductive hydrogels as multifunctional muscle-mimicking biomaterials: Graphene-incorporated hydrogels directly patterned with femtosecond laser …
Multifunctional biomaterials that can provide physical, electrical, and structural cues to cells
and tissues are highly desirable to mimic the important characteristics of native tissues and …
and tissues are highly desirable to mimic the important characteristics of native tissues and …
Anisotropically aligned cell‐laden nanofibrous bundle fabricated via cell electrospinning to regenerate skeletal muscle tissue
For muscle regeneration, a uniaxially arranged micropattern is important to mimic the
structure of the natural extracellular matrix. Recently, cell electrospinning (CE) has been …
structure of the natural extracellular matrix. Recently, cell electrospinning (CE) has been …