The pan-genome of Aspergillus fumigatus provides a high-resolution view of its population structure revealing high levels of lineage-specific diversity driven by …
Aspergillus fumigatus is a deadly agent of human fungal disease where virulence
heterogeneity is thought to be at least partially structured by genetic variation between …
heterogeneity is thought to be at least partially structured by genetic variation between …
Genetic engineering and synthetic genomics in yeast to understand life and boost biotechnology
D Schindler - Bioengineering, 2020 - mdpi.com
The field of genetic engineering was born in 1973 with the “construction of biologically
functional bacterial plasmids in vitro”. Since then, a vast number of technologies have been …
functional bacterial plasmids in vitro”. Since then, a vast number of technologies have been …
Genomic Adaptations of Saccharomyces Genus to Wine Niche
E García-Ríos, JM Guillamón - Microorganisms, 2022 - mdpi.com
Wine yeast have been exposed to harsh conditions for millennia, which have led to adaptive
evolutionary strategies. Thus, wine yeasts from Saccharomyces genus are considered an …
evolutionary strategies. Thus, wine yeasts from Saccharomyces genus are considered an …
Bayesian genome scale modelling identifies thermal determinants of yeast metabolism
The molecular basis of how temperature affects cell metabolism has been a long-standing
question in biology, where the main obstacles are the lack of high-quality data and methods …
question in biology, where the main obstacles are the lack of high-quality data and methods …
Transporter proteins as ecological assets and features of microbial eukaryotic Pangenomes
Here we review two connected themes in evolutionary microbiology:(a) the nature of gene
repertoire variation within species groups (pangenomes) and (b) the concept of metabolite …
repertoire variation within species groups (pangenomes) and (b) the concept of metabolite …
Performance of regression models as a function of experiment noise
Background: A challenge in developing machine learning regression models is that it is
difficult to know whether maximal performance has been reached on the test dataset, or …
difficult to know whether maximal performance has been reached on the test dataset, or …
A Pan-Draft Metabolic Model Reflects Evolutionary Diversity across 332 Yeast Species
Yeasts are increasingly employed in synthetic biology as chassis strains, including
conventional and non-conventional species. It is still unclear how genomic evolution …
conventional and non-conventional species. It is still unclear how genomic evolution …
Haploid Genome Analysis Reveals a Tandem Cluster of Four HSP20 Genes Involved in the High-Temperature Adaptation of Coriolopsis trogii
L Wang, B Liao, L Gong, S Xiao… - Microbiology Spectrum, 2021 - Am Soc Microbiol
Coriolopsis trogii is a typical thermotolerant basidiomycete fungus, but its thermotolerance
mechanisms are currently unknown. In this study, two monokaryons of C. trogii strain Ct001 …
mechanisms are currently unknown. In this study, two monokaryons of C. trogii strain Ct001 …
Combined Pan-, Population-, and Phylo-Genomic Analysis of Aspergillus fumigatus Reveals Population Structure and Lineage-Specific Diversity
Aspergillus fumigatus is a deadly agent of human fungal disease, where virulence
heterogeneity is thought to be at least partially structured by genetic variation between …
heterogeneity is thought to be at least partially structured by genetic variation between …
Meta-analysis of dispensable essential genes and their interactions with bypass suppressors
C Pons, J van Leeuwen - Life Science Alliance, 2024 - life-science-alliance.org
Genes have been historically classified as essential or non-essential based on their
requirement for viability. However, genomic mutations can sometimes bypass the …
requirement for viability. However, genomic mutations can sometimes bypass the …