Native valve, prosthetic valve, and cardiac device-related infective endocarditis: A review and update on current innovative diagnostic and therapeutic strategies

JJP Kouijzer, DJ Noordermeer… - Frontiers in cell and …, 2022 - frontiersin.org
Infective endocarditis (IE) is a life-threatening microbial infection of native and prosthetic
heart valves, endocardial surface, and/or indwelling cardiac device. Prevalence of IE is …

Infection imaging: focus on new tracers?

W Roll, A Faust, S Hermann… - Journal of Nuclear …, 2023 - Soc Nuclear Med
Infections account for relevant morbidity and mortality, especially if the cardiovascular
system is affected. Clinical manifestations are often unspecific, resulting in a challenging …

Evaluating the performance of pathogen-targeted positron emission tomography radiotracers in a rat model of vertebral discitis-osteomyelitis

MFL Parker, M López-Álvarez, AA Alanizi… - The Journal of …, 2023 - academic.oup.com
Background Vertebral discitis-osteomyelitis (VDO) is a devastating infection of the spine that
is challenging to distinguish from noninfectious mimics using computed tomography and …

The role of multimodality imaging in patients with congenital heart disease and infective endocarditis

S Moscatelli, I Leo, F Bianco, E Surkova, T Pezel… - Diagnostics, 2023 - mdpi.com
Infective endocarditis (IE) represents an important medical challenge, particularly in patients
with congenital heart diseases (CHD). Its early and accurate diagnosis is crucial for effective …

[HTML][HTML] Preclinical evaluation of 2-[18F] fluorodeoxysorbitol as a tracer for targeted imaging of Enterobacterales infection

LM Braams, JWA Sijbesma, HH Boersma… - International Journal of …, 2023 - Elsevier
Abstract Fluorine-18-fluorodeoxyglucose ([18 F] FDG) positron emission tomography (18 F-
FDG-PET) is widely used for the detection of inflammatory and infectious diseases. Although …

Real world experience of therapeutic monitoring of medically treated prosthetic valve infective endocarditis by 18F-FDG-PET/CT

L Bucy, ML Erpelding, C Boursier, B Lefevre… - Journal of Nuclear …, 2023 - Springer
Abstract Introduction 18F-FDG-PET/CT is recommended to improve the diagnosis of
prosthetic valve infective endocarditis (PVIE) and is a major criterion in the ESC-2015 …

New synthesis of 6″‐[18F]fluoromaltotriose for positron emission tomography imaging of bacterial infection

MT Gabr, T Haywood, G Gowrishankar… - Journal of Labelled …, 2020 - Wiley Online Library
6 ″‐[18F] fluoromaltotriose is a positron emission tomography tracer that can differentiate
between bacterial infection and inflammation in vivo. Bacteria‐specific uptake of 6 ″‐[18F] …

Imaging of bacterial infections

AA Ordoñez, SK Jain - Molecular Imaging, 2021 - Elsevier
Bacterial infections remain a major threat to human health. However, conventional tools
currently used for diagnosis require clinical samples which may not be informative for deep …

Sanjiv Sam Gambhir, MD, PhD (1962-2020)

JC Wu, M Wardak, IY Chen - Journal of Nuclear Cardiology, 2021 - Springer
''I remain optimistic that the fundamental basic science that we all continue to do leads to
new technologies that will help re-engineer our own bodies so that we can detect disease …