Physics-based computational models of the cardiovascular system are increasingly used to
simulate hemodynamics, tissue mechanics, and physiology in evolving healthy and …

The human heart is enclosed in the pericardial cavity. The pericardium consists of a layered
thin sac and is separated from the myocardium by a thin film of fluid. It provides a fixture in …

Introduction Atrial fibrillation (AF) is an increasingly prevalent and significant worldwide
health problem. Manifested as an irregular atrial electrophysiological activation, it is …

Cardiac electrophysiology simulations are numerically challenging because of the
propagation of a steep electrochemical wave front and thus require discretizations with small …

Abstract Knowledge of appropriate local fiber architecture is necessary to simulate patient‐
specific electromechanics in the human heart. However, it is not yet possible to reliably …

Purpose Atrial fibrillation is one of the most frequent cardiac arrhythmias in the industrialized
world and ablation therapy is the method of choice for many patients. However, ablation …

Cardiovascular diseases remain one of the largest causes of death worldwide. The lethal
pathologies often occur due to atherosclerosis, clot formation and cardiac arrhythmia. It turns …

Computational methods for modeling of patient-specific mechanics of the heart and the
circulatory system are developed. The 3-dimensionally resolved heart is coupled to a …

In this work, a computational model is developed to simulate the cardiac cycle using a
patient-specific four-chamber geometry. The enhanced accuracy of efficient boundary …

The human heart is enclosed in the pericardial cavity. The pericardium consists of a layered
thin sac and is separated from the myocardium by a thin film of fluid. It provides a fixture in …