Recent applications of the multicomponent synthesis for bioactive pyrazole derivatives

D Becerra, R Abonia, JC Castillo - Molecules, 2022 - mdpi.com
Pyrazole and its derivatives are considered a privileged N-heterocycle with immense
therapeutic potential. Over the last few decades, the pot, atom, and step economy (PASE) …

Synthesis of pyrano [2, 3‐c] pyrazoles: A review

S Sikandar, AF Zahoor - Journal of Heterocyclic Chemistry, 2021 - Wiley Online Library
One‐pot synthesis of pyrano [2, 3‐c] pyrazole derivatives via two or multicomponent
condensation of β‐ketoesters, hydrazine monohydrate/phenyl hydrazine, malononitrile, and …

Fe3O4/GO@ melamine-ZnO nanocomposite: A promising versatile tool for organic catalysis and electrical capacitance

R Eivazzadeh-Keihan, R Taheri-Ledari… - Colloids and Surfaces A …, 2020 - Elsevier
Herein, an efficient versatile nanocomposite constructed of melamine-functionalized
graphene oxide nano-sheets (GO@ melamine), iron oxide nanoparticles (Fe 3 O 4 NPs) …

A New Pathway for the Preparation of Pyrano[2,3-c]pyrazoles and molecular Docking as Inhibitors of p38 MAP Kinase

HT Nguyen, MNH Truong, TV Le, NT Vo… - ACS …, 2022 - ACS Publications
We report a new pathway to synthesize pyrano [2, 3-c] pyrazoles and their binding mode to
p38 MAP kinase. Pyrano [2, 3-c] pyrazole derivatives have been prepared through a four …

Preparation of Fe3O4@ Carrageenan-Metformin nanoparticles as a new bio-inspired magnetic nanocatalyst for the synthesis of dihydropyrano [2, 3-c] pyrazoles

F Heydari, M Bakhtiarian, MM Khodaei - Materials Science and …, 2023 - Elsevier
Abstract k-Carrageenan (Carr) is a significant constituent of red seaweeds with benign
nature and easy modification due to available sulfate and hydroxyl functionalities. The …

Synthesis and pharmacological properties of polysubstituted 2-amino-4H-pyran-3-carbonitrile derivatives

Z Tashrifi, M Mohammadi-Khanaposhtani… - Molecular Diversity, 2020 - Springer
Amino-3-cyano-4 H-chromenes are structural core motifs that received increasing attention
in the last years due to their interesting potential pharmacological properties. In this review …

Hydrolyzed Arabic gum-grafted-polyacrylonitrile@ zinc ferrite nanocomposite as an efficient biocatalyst for the synthesis of pyranopyrazoles derivatives

F Hassanzadeh-Afruzi, MM Salehi, G Heidari… - Journal of Molecular …, 2023 - Elsevier
A catalytic methodology for the effective synthesis of pyrazolopyrazole derivatives using a
combination of hydrolyzed Arabic gum-g-polyacrylonitrile/ZnFe 2 O 4 (Hyd AG-g-PAN/ZnFe …

[PDF][PDF] Synthesis, characterization and evaluation of some Pyranopyrazole derivatives as multifunction additives for medium lubricating Oils

AR Salih, ZAK Al-Messri - Iraqi Journal of Science, 2022 - iasj.net
The current work involves synthesis of 6-amino-4-(4-hydroxyl-3-methoxyphenyl)-3-methyl-1-
phenyl-1, 4- dihydropyrano [2, 3-c] pyrazole-5-carbonitrile (2) by condensation of 2-(4 …

Synthesis of 1, 4-dihydropyrano [2, 3-c] pyrazole derivatives and exploring molecular and cytotoxic properties based on DFT and molecular docking studies

AM Fouda, MAA El-Nassag, AA Elhenawy… - Journal of Molecular …, 2022 - Elsevier
One-pot multicomponent reaction of ethyl 3-oxobutanoate or ethyl 3-oxo-3-
phenylpropanoate, hydrazine hydrate, malononitrile, various aldehydes in ethanolic …

Current status and structure activity relationship of privileged azoles as antifungal agents (2016–2020)

A Ahmadi, E Mohammadnejadi, P Karami… - International Journal of …, 2022 - Elsevier
Fungal infections have greatly contributed to infectious-related deaths in the past century.
This issue has become worse with the advent of immunity-impairing conditions such as HIV …