Insight on development of oxazole and imidazole derivatives as COX inhibitors with anti-inflammatory effects
NSAIDs are the most famous anti-inflammatory drugs and are mainly classified into two
groups, the non-selective NSAIDs that inhibit both COX-1 and COX-2 enzymes with side …
groups, the non-selective NSAIDs that inhibit both COX-1 and COX-2 enzymes with side …
Synthesis, Identification, Antioxidant, Molecular Docking, and In Silico ADME Study for Some New Derivatives Containing Thiourea Moiety
AA Maryoosh, OHR Al-Jeilawi - Russian Journal of Bioorganic Chemistry, 2024 - Springer
Objective: Synthesized a series of new thiourea (TU) derivatives, tested their antioxidant
activity, and investigated their expected biological activity by theoretical study …
activity, and investigated their expected biological activity by theoretical study …
COX-2 Enzyme Inhibitors Study and Efficacy Pharmacokinetic by Molecular Docking for some New Heterocyclic Rings Driver from Levofloxacin Drug
MI Khalaf - Russian Journal of Bioorganic Chemistry, 2023 - Springer
Assay methods using cyclooxygenase fluorescence inhibitors and the standard drug
levofloxacin were used to determine the anti-inflammatory profile of Triazole, Triazine …
levofloxacin were used to determine the anti-inflammatory profile of Triazole, Triazine …
Design, Molecular Docking and Molecular Dynamic Simulation of New Heterocyclic Derivatives as Potential Anticancer Agents
DA Abdulqader, MF Mahdi - Al-Rafidain Journal of Medical Sciences (ISSN …, 2024 - ajms.iq
Research Article Design, Molecular Docking and Molecular Dynamic Simulation of New
Heterocyclic Derivatives as Potential Antican Page 1 Abdulqader & Mahdi Heterocyclic …
Heterocyclic Derivatives as Potential Antican Page 1 Abdulqader & Mahdi Heterocyclic …
[PDF][PDF] Modification and Characterization of Some New Levofloxacin Heterocyclic Derivatives as COX-2 Enzyme Inhibitors and Evaluate Their Efficacy …
MM Rabeaa, MI Khalaf - Baghdad Science Journal, 2024 - iasj.net
In order to predict anti-inflammatory activity against (COX-2) and expect their anticancer
potential, new 1, 2, 4-triazole-5-thiol, Oxadiazole, and Imide derivatives were modified …
potential, new 1, 2, 4-triazole-5-thiol, Oxadiazole, and Imide derivatives were modified …
[PDF][PDF] Synthesis, Molecular Docking, Characterization, and Preliminary Evaluation of Some New 1, 3-Diazetidin-2-One Derivatives as Anticancer Agents
MF Mahdi, AK Khan - Al Mustansiriyah Journal of Pharmaceutical …, 2024 - iasj.net
A series of novel 1, 3-diazetidin-2-one derivatives were designed, synthesized, and
evaluated preliminary (In Vitro) for their cytotoxic activity against the lung (A549) cancer cell …
evaluated preliminary (In Vitro) for their cytotoxic activity against the lung (A549) cancer cell …