The degree of nerve regeneration after peripheral nerve injury can be altered by the
microenvironment at the site of injury. Stem cells and vascularity are postulated to be a part …

Introduction: The clinical use of tacrolimus is characterized by many side effects which
include neurotoxicity. In contrast, tacrolimus has also shown to have neuroregenerative …

Tremor is a common side effect of tacrolimus correlated with peak‐dose drug concentration.
LCPT, a novel, once‐daily, extended‐release formulation of tacrolimus, has a reduced C …

Introduction: Renal transplantation is the best therapy for patients with end-stage renal
disease. To avoid graft rejection, adequate immunosuppressive therapy is crucial …

Calcineurin inhibitors such as cyclosporine and tacrolimus are immunosuppressant drugs
that are known to induce tremors. Non-calcineurin inhibitors such as sirolimus and …

Introduction Tremor is the most frequent and disabling neurological side effect under
Calcineurin inhibitor-induced immunosuppression, but no studies have defined its …

Local immunomodulation has shown the potential to control the immune response in a site-
specific manner for wound healing, cancer, allergy, and cell transplantation, thus abrogating …

The human microbiome is associated with human health and disease. Exogenous
compounds, including pharmaceutical products, are also known to be affected by the …

The application of scaffold‐based stem cell transplantation to enhance peripheral nerve
regeneration has great potential. Recently, the neuroregenerative potential of tacrolimus (a …

Background: Tacrolimus is a potent immunosuppressant drug commonly used after solid
organ transplant surgery. The use of this drug is frequently associated with the emergence of …