Plant lectins as medical tools against digestive system cancers

LE Estrada-Martínez, U Moreno-Celis… - International journal of …, 2017 - mdpi.com
Digestive system cancers—those of the esophagus, stomach, small intestine, colon-rectum,
liver, and pancreas—are highly related to genetics and lifestyle. Most are considered highly …

MiR-23b-3p reduces the proliferation, migration and invasion of cervical cancer cell lines via the reduction of c-Met expression

GE Campos-Viguri, O Peralta-Zaragoza… - Scientific reports, 2020 - nature.com
Malignant transformation and progression in cancer is associated with the altered
expression of multiple miRNAs, which are considered as post-transcriptional regulators of …

Tepary Bean (Phaseolus acutifolius) Lectins Induce Apoptosis and Cell Arrest in G0/G1 by P53(Ser46) Phosphorylation in Colon Cancer Cells

U Moreno-Celis, FJ López-Martínez… - Molecules, 2020 - mdpi.com
A Tepary bean lectin fraction (TBLF) has been studied because it exhibits differential
cytotoxic and anticancer effects on colon cancer. The present work focuses on the …

Antioxidant Activity and Anticarcinogenic Effect of Extracts from Bouvardia ternifolia (Cav.) Schltdl.

C Valadez-Vega, O Lugo-Magaña… - Life, 2023 - mdpi.com
According to the available ethnobotanical data, the Bouvardia ternifolia plant has long been
used in Mexican traditional medicine to relieve the symptoms of inflammation. In the present …

Potential role of herbal-and bacterial-derived peptides against colorectal cancer

S Abdoullahi, A Jahangiri, R Halabian - Revista Brasileira de …, 2022 - Springer
Despite recent advances in the prevention, diagnosis, and treatment of colorectal cancer as
the third cause of cancer death, the development of refractory tumor cells results in low …

Pea lectin inhibits cell growth by inducing apoptosis in SW480 and SW48 cell lines

F Islam, V Gopalan, AKY Lam, SR Kabir - International journal of biological …, 2018 - Elsevier
Globally, colorectal cancer is the third most common type of malignant tumor, after lung and
breast. Here anticancer property of pea lectin was evaluated against colorectal cancer cell …

Cytotoxic Proteins from King Tuber Oyster Medicinal Mushroom, Pleurotus tuber-regium (Agaricomycetes), Sclerotium against Human MDA-MB-231 Breast Cancer …

E Abdullah, NZ Abidin… - International Journal of …, 2022 - dl.begellhouse.com
Numerous studies have reported the vast medicinal values of proteins from mushrooms. The
present study aimed to investigate the potential of protein extracts from the sclerotium of …

Phaseolus acutifolius Lectin Fractions Exhibit Apoptotic Effects on Colon Cancer: Preclinical Studies Using Dimethilhydrazine or Azoxi-Methane as Cancer Induction …

U Moreno-Celis, J López-Martínez, A Blanco-Labra… - Molecules, 2017 - mdpi.com
Phaseolus acutifolius (Tepary bean) lectins have been studied as cytotoxic molecules on
colon cancer cells. The toxicological profile of a Tepary bean lectin fraction (TBLF) has …

[HTML][HTML] Purification, Structural Characterization, and Bioactivity of Amaranthus hypochondriacus Lectin

MF Resendiz-Otero, A Bernardino-Nicanor… - Molecules, 2024 - mdpi.com
Lectin extracted from Amaranthus hypochondriacus was purified using an affinity column
with an agarose-fetuin matrix specific to the lectin of interest. Purification was confirmed by …

[HTML][HTML] Directed Mutagenesis for Arginine Substitution of a Phaseolus acutifolius Recombinant Lectin Disrupts Its Cytotoxic Activity

D Martínez-Alarcón, JL Castro-Guillén… - International …, 2024 - pmc.ncbi.nlm.nih.gov
Recently, we reported that a recombinant Tepary bean (Phaseolus acutifolius) lectin (rTBL-
1) induces apoptosis in colon cancer cell lines and that cytotoxicity was related to differential …