Unconventional animal models for traumatic brain injury and chronic traumatic encephalopathy
NL Ackermans, M Varghese, B Wicinski… - Journal of …, 2021 - Wiley Online Library
Traumatic brain injury (TBI) is one of the main causes of death worldwide. It is a complex
injury that influences cellular physiology, causes neuronal cell death, and affects molecular …
injury that influences cellular physiology, causes neuronal cell death, and affects molecular …
Immune-endocrine interactions in the pathophysiology of sleep-wake disturbances following traumatic brain injury: A narrative review
RK Rowe, GS Griesbach - Brain Research Bulletin, 2022 - Elsevier
Following a traumatic brain injury (TBI), sleep-wake disturbances are one of the most
prevalent and debilitating symptoms. A better understanding of the impact that sleep …
prevalent and debilitating symptoms. A better understanding of the impact that sleep …
Long-term effects of blast exposure: a functional study in rats using an advanced blast simulator
P Arun, DM Wilder, O Eken, R Urioste… - Journal of …, 2020 - liebertpub.com
Anecdotal observations of blast victims indicate that significant neuropathological and
neurobehavioral defects may develop at later stages of life. To pre-clinically model this …
neurobehavioral defects may develop at later stages of life. To pre-clinically model this …
Behavioral and myelin-related abnormalities after blast-induced mild traumatic brain injury in mice
In civilian and military settings, mild traumatic brain injury (mTBI) is a common consequence
of impacts to the head, sudden blows to the body, and exposure to high-energy atmospheric …
of impacts to the head, sudden blows to the body, and exposure to high-energy atmospheric …
Hippocampal-dependent cognitive dysfunction following repeated diffuse rotational brain injury in male and female mice
Cognitive dysfunction is a common, often long-term complaint following acquired traumatic
brain injury (TBI). Cognitive deficits suggest dysfunction in hippocampal circuits. The goal of …
brain injury (TBI). Cognitive deficits suggest dysfunction in hippocampal circuits. The goal of …
Expression of GFAP and tau following blast exposure in the cerebral cortex of ferrets
SC Schwerin, M Chatterjee… - … of Neuropathology & …, 2021 - academic.oup.com
Blast exposures are a hallmark of contemporary military conflicts. We need improved
preclinical models of blast traumatic brain injury for translation of pharmaceutical and …
preclinical models of blast traumatic brain injury for translation of pharmaceutical and …
Persistent hypersomnia following repetitive mild experimental traumatic brain injury: Roles of chronic stress and sex differences
E Portillo, X Zi, Y Kim, LB Tucker, A Fu… - Journal of …, 2023 - Wiley Online Library
Traumatic brain injury (TBI) is often more complicated than a single head injury. An extreme
example of this point may be military service members who experience a spectrum of …
example of this point may be military service members who experience a spectrum of …
Actigraphic evidence of persistent sleep disruption following repetitive mild traumatic brain injury in a gyrencephalic model
SC Schwerin, N Breehl, A Obasa, Y Kim… - Cerebral …, 2023 - academic.oup.com
We studied the effect of multimodal traumatic brain injuries on daily sleep/activity patterns
and related histology. Gyrencephalic ferrets wore actigraphs and received military-relevant …
and related histology. Gyrencephalic ferrets wore actigraphs and received military-relevant …
[HTML][HTML] Sex as a biological variable in preclinical modeling of blast-related traumatic brain injury
Approaches to furthering our understanding of the bioeffects, behavioral changes, and
treatment options following exposure to blast are a worldwide priority. Of particular need is a …
treatment options following exposure to blast are a worldwide priority. Of particular need is a …
[HTML][HTML] Limbic responses following shock wave exposure in male and female mice
EH McNamara, LB Tucker, J Liu, AH Fu… - Frontiers in Behavioral …, 2022 - frontiersin.org
Blast traumatic brain injury (bTBI) presents a serious threat to military personnel and often
results in psychiatric conditions related to limbic system dysfunction. In this study, the …
results in psychiatric conditions related to limbic system dysfunction. In this study, the …