Vitamin C: the known and the unknown and Goldilocks

SJ Padayatty, M Levine - Oral diseases, 2016 - Wiley Online Library
Vitamin C (Ascorbic Acid), the antiscorbutic vitamin, cannot be synthesized by humans and
other primates, and has to be obtained from diet. Ascorbic acid is an electron donor and acts …

Recent updates on bioaccessibility of phytonutrients

N Thakur, P Raigond, Y Singh, T Mishra… - Trends in Food Science …, 2020 - Elsevier
Background Fruits and vegetables are rich source of phytonutrients. These phytonutrients
are present in high concentrations in raw form, and decrease to some extent after …

Vitamin C pharmacokinetics: implications for oral and intravenous use

SJ Padayatty, H Sun, Y Wang, HD Riordan… - Annals of internal …, 2004 - acpjournals.org
Background: Vitamin C at high concentrations is toxic to cancer cells in vitro. Early clinical
studies of vitamin C in patients with terminal cancer suggested clinical benefit, but 2 double …

Potential mechanisms of action for vitamin C in cancer: reviewing the evidence

MCM Vissers, AB Das - Frontiers in physiology, 2018 - frontiersin.org
Whether vitamin C (ascorbate) has a role to play as an anti-cancer agent has been debated
for decades. Ascorbate has been used by cancer patients in an unregulated environment …

The active role of vitamin C in mammalian iron metabolism: much more than just enhanced iron absorption!

DJR Lane, DR Richardson - Free radical biology and medicine, 2014 - Elsevier
Ascorbate is a cofactor in numerous metabolic reactions. Humans cannot synthesize
ascorbate owing to inactivation of the gene encoding the enzyme l-gulono-γ-lactone …

Vitamin C: update on physiology and pharmacology

J Mandl, A Szarka, G Banhegyi - British journal of …, 2009 - Wiley Online Library
Although ascorbic acid is an important water‐soluble antioxidant and enzyme cofactor in
plants and animals, humans and some other species do not synthesize ascorbate due to the …

The nutritional and pharmacological consequences of obesity surgery

J Stein, C Stier, H Raab… - Alimentary pharmacology & …, 2014 - Wiley Online Library
Background Obesity surgery is acknowledged as a highly effective therapy for morbidly
obese patients. Beneficial short‐term effects on common comorbidities are practically …

Ascorbic acid: its role in immune system and chronic inflammation diseases

A Sorice, E Guerriero, F Capone… - Mini reviews in …, 2014 - ingentaconnect.com
Ascorbic acid (AA), also known as vitamin C, was initially identified as the factor preventing
the scurvy disease, and became very popular for its antioxidant properties. It is an important …

[HTML][HTML] Nutrition, anabolism, and the wound healing process: an overview

RH Demling - Eplasty, 2009 - ncbi.nlm.nih.gov
Objective: To develop a clear, concise, and up-to-date treatise on the role of anabolism from
nutrition in wound healing. Special emphasis was to be placed on the effect of the stress …

[图书][B] Oxygen: the molecule that made the world

N Lane - 2002 - books.google.com
In Oxygen, Nick Lane takes the reader on an enthralling journey as he unravels the
unexpected ways in which oxygen spurred the evolution of life and death. He shows how …