Peroxisomes are key metabolic organelles, which contribute to cellular lipid metabolism, eg
the β-oxidation of fatty acids and the synthesis of myelin sheath lipids, as well as cellular …

ATP-binding cassette (ABC) transporters constitute one of the largest superfamilies of
conserved proteins from bacteria to mammals. In humans, three members of this family are …

Malignant gliomas (MG) are highly infiltrative tumors that consistently recur despite
aggressive treatment. Brain fatty acid-binding protein (FABP7), which binds …

Glioblastoma multiforme (GBM) or grade IV astrocytoma is the most common and lethal adult
malignant brain tumor. The present study was conducted to investigate the alterations in the …

GBM, the most common and aggressive malignant primary brain tumors which needs new
research approach to reveal the underline molecular mechanism of tumor progression. The …

Glioblastoma multiforme (GBM) represents the most severe type of glioma, the most
common brain tumor. Their malignancy shows a relationship with an increased proliferation …

Head and neck paragangliomas (HNPGLs) are rare tumors that may cause important
morbidity, because of their tendency to infiltrate the skull base. At present, surgery is the only …

Energy homeostasis is crucial for cell fate, since all cellular activities are strongly dependent
on the balance between catabolic and anabolic pathways. In particular, the modulation of …

Abstract Glioblastoma (GBM, Grade IV astrocytoma) is the most common and most
aggressive of the primary malignant brain tumors in adults. Hypoxia is a distinct feature in …

Glioblastoma (GB) is the most common cancer in the brain and with an increasing incidence.
Despite major advances in the field, there is no curative therapy for GB to date. Many solid …