Lipids are a fundamental class of organic molecules implicated in a wide range of biological
processes related to their structural diversity, and based on this can be broadly classified …

Neural membranes contain several classes of glycerophospholipids which turnover at
different rates with respect to their structure and localization in different cells and …

Mitochondrial membrane phospholipids are essential for the mitochondrial architecture, the
activity of respiratory proteins, and the transport of proteins into the mitochondria. The …

Astrocytes are the most abundant glial cell in the central nervous system and are involved in
multiple processes including metabolic homeostasis, blood brain barrier regulation and …

Objective Deficient cerebral inhibition is a pathophysiological brain deficit related to poor
sensory gating and attention in schizophrenia and other disorders. Cerebral inhibition …

Docosahexaenoic acid (DHA), an omega-3 polyunsaturated fatty acid, is an essential
component of membrane phosphatides and has been implicated in cognitive functions. Low …

Twelve mildly hypertensive but otherwise normal fasting subjects received each of four
treatments in random order: CDP-choline (citicoline; 500, 2000, and 4000 mg) or a placebo …

The synthesis of brain phosphatidylcholine may utilize three circulating precursors: choline;
a pyrimidine (eg, uridine, converted via UTP to brain CTP); and a PUFA (eg …

New brain synapses form when a postsynaptic structure, the dendritic spine, interacts with a
presynaptic terminal. Brain synapses and dendritic spines, membrane-rich structures, are …

Objective: α7-Nicotinic receptors are involved in the final maturation of GABA inhibitory
synapses before birth. Choline at levels found in the amniotic fluid is an agonist at α7 …