▪ Abstract This paper reviews the common statistical techniques employed to analyze
survival data in public health research. Due to the presence of censoring, the data are not …

Clustered survival data are encountered in many scientific disciplines including human and
veterinary medicine, biology, epidemiology, public health and demography. Frailty models …

Background Young-onset cancer is a hallmark of many familial cancer syndromes, yet the
implications of young-onset disease in predicting risk of pancreatic cancer among familial …

To characterize cancer risk in heterozygous p53 mutation carriers, we analyzed cancer
incidence in 56 germline p53 mutation carriers and 3,201 noncarriers from 107 kindreds …

Protein sequence contains clues to its function. Functional prediction from sequence
presents a challenge particularly for proteins that have low or no sequence similarity to …

Background and aims: Peutz-Jeghers syndrome (PJS) is a dominantly inherited disorder
often caused by mutations in STK11. Time to onset of symptoms was characterised for a …

We recently observed a significantly increased risk for lung cancer in carriers of p53
germline mutations. Because cigarette smoking is known to play an important role in …

Proportional hazards models and their extensions (models with timedependent covariates,
models with time dependent regression coefficients, models with random coefficients and …

For the analysis of clustered survival data, two different types of model that take the
association into account are commonly used: frailty models and copula models. Frailty …

Background: Glenohumeral chondrolysis is a complication of arthroscopic shoulder surgery
characterized by the dissolution of the articular cartilage of the glenoid and the humeral …