Stroke is a leading cause of morbidity and mortality worldwide, and consists of two types,
ischemic and hemorrhagic. Currently, there is no effective treatment to increase the survival …

Stroke is a leading cause of death worldwide. Ischemic stroke is caused by blockage of
blood vessels in the brain leading to tissue death, while intracerebral hemorrhage (ICH) …

Organ ischemia with inadequate oxygen supply followed by reperfusion (which initiates a
complex of inflammatory responses and oxidative stress) occurs in different clinical …

Background Microglia cells continuously survey the healthy brain in a ramified morphology
and, in response to injury, undergo progressive morphological and functional changes that …

Hepatic ischemia‐reperfusion injury (IRI), in which an insufficient oxygen supply followed by
reperfusion leads to an inflammatory network and oxidative stress in disease tissue to cause …

Abstract According to the World Health Organization, major depression will become the
leading cause of disability worldwide by the year 2030. Despite extensive research into the …

Large magnetic nanoparticles or aggregates are advantageous in their magnetic resonance
properties over ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles (NPs), but …

Inflammation can extend ischemic brain injury and adversely affect outcome in experimental
animal models. A key difficulty in translating animal studies to humans is the lack of a …

Microglia are resident CNS immune cells that are active sensors in healthy brain and
versatile effectors under pathological conditions. Cerebral ischemia induces a robust …

Inflammation has a pivotal role in the pathogenesis of ischemic stroke, and recent studies
posit that inflammation acts as a double‐edged sword, not only detrimentally augmenting …