A comprehensive analysis and anti-cancer activities of quercetin in ROS-mediated cancer and cancer stem cells

P Biswas, D Dey, PK Biswas, TI Rahaman… - International journal of …, 2022 - mdpi.com
Reactive oxygen species (ROS) induce carcinogenesis by causing genetic mutations,
activating oncogenes, and increasing oxidative stress, all of which affect cell proliferation …

Using ncRNAs as tools in Cancer diagnosis and treatment—the way towards personalized medicine to improve patients' health

R Piergentili, G Basile, C Nocella, R Carnevale… - International journal of …, 2022 - mdpi.com
Although the first discovery of a non-coding RNA (ncRNA) dates back to 1958, only in recent
years has the complexity of the transcriptome started to be elucidated. However, its …

Quercetin nanoformulations: a promising strategy for tumor therapy

X Zang, M Cheng, X Zhang, X Chen - Food & Function, 2021 - pubs.rsc.org
Phytochemicals as dietary constituents are being widely explored for the prevention and
treatment of various diseases. Quercetin, a major constituent of various dietary products, has …

Pterostilbene prevents hepatocyte epithelial‐mesenchymal transition in fructose‐induced liver fibrosis through suppressing miR‐34a/Sirt1/p53 and TGF‐β1/Smads …

L Song, TY Chen, XJ Zhao, Q Xu… - British journal of …, 2019 - Wiley Online Library
Background and Purpose Excessive fructose consumption is a risk factor for liver fibrosis.
Pterostilbene protects against liver fibrosis. Here, we investigated the potential role and the …

Dietary phytochemicals as epigenetic modifiers in cancer: Promise and challenges

E Shankar, R Kanwal, M Candamo, S Gupta - Seminars in cancer biology, 2016 - Elsevier
The influence of diet and environment on human health has been known since ages. Plant-
derived natural bioactive compounds (phytochemicals) have acquired an important role in …

MicroRNA targeting by quercetin in cancer treatment and chemoprotection

DH Kim, H Khan, H Ullah, STS Hassan… - Pharmacological …, 2019 - Elsevier
A growing number of evidences from clinical and preclinical studies have shown that
dysregulation of microRNA (miRNA) function contributes to the progression of cancer and …

Targeted delivery of quercetin by biotinylated mixed micelles for non-small cell lung cancer treatment

K Li, X Zang, X Meng, Y Li, Y Xie, X Chen - Drug Delivery, 2022 - Taylor & Francis
Lung cancer is the leading cause of cancer death world-wide and its treatment remains a
challenge in clinic, especially for non-small cell lung cancer (NSCLC). Thus, more effective …

Molecular mechanisms of action of quercetin in cancer: recent advances

D Kashyap, S Mittal, K Sak, P Singhal, HS Tuli - Tumor Biology, 2016 - Springer
In the last few decades, the scientific community has discovered an immense potential of
natural compounds in the treatment of dreadful diseases such as cancer. Besides the …

Long non-coding RNA HNF1A-AS1 mediated repression of miR-34a/SIRT1/p53 feedback loop promotes the metastatic progression of colon cancer by functioning as …

C Fang, S Qiu, F Sun, W Li, Z Wang, B Yue, X Wu… - Cancer letters, 2017 - Elsevier
In recent years, accumulating evidence indicates that long noncoding RNAs (lncRNAs) have
emerged as powerful influence factors in the progression of multiple malignancies …

RAS/RAF/MEK/ERK, PI3K/PTEN/AKT/mTORC1 and TP53 pathways and regulatory miRs as therapeutic targets in hepatocellular carcinoma

SM Akula, SL Abrams, LS Steelman… - Expert Opinion on …, 2019 - Taylor & Francis
Introduction: Hepatocellular carcinoma (HCC) is a significant problem globally because of
viral infections and the increasing incidence of obesity and fatty liver disease. However, it is …