Direct (hetero) arylation polymerization (DHAP) has recently been established as an
environmentally benign method for the preparation of conjugated polymers. This synthetic …

The site-selective formation of carbonrcarbon bonds through direct functionalizations of
otherwise unreactive carbonrhydrogen bonds constitutes an economically attractive strategy …

Cross-coupling reactions, which were discovered almost 50 years ago, are widely used in
both industry and academia. Even though cross-coupling reactions now represent mature …

Metal-catalysed C–H bond functionalisation has had a significant impact on how chemists
make molecules. Translating the methodological developments to their use in the assembly …

C− H activation reactions with high catalyst turnover numbers are still very rare in the
literature and 10 mol% is a common catalyst loading in this field. We offer a representative …

Kinetic Isotope Effects in the Study of Organometallic Reaction Mechanisms | Chemical
Reviews ACS ACS Publications C&EN CAS Find my institution Log In Chemical Reviews ACS …

The biaryl structural motif is a predominant feature in many pharmaceutically relevant and
biologically active compounds. As a result, for over a century1 organic chemists have sought …

Homogeneous palladium catalysis has gained enormous relevance in various coupling
reactions such as Heck, Stille, Suzuki, Sonogashira, and Buchwald-Hartwig reactions. Many …

A new palladium-catalyzed arylation process based on C− H activation has been
developed. The utilization of pyridine-containing directing groups allows the β-arylation of …

The cleavage of aromatic C–H bonds promoted by a metal and an intramolecular base has
been described over 50 years ago. Herein, discussion of selected mechanistic studies of this …