Nicotine in inflammatory diseases: anti-inflammatory and pro-inflammatory effects

W Zhang, H Lin, M Zou, Q Yuan, Z Huang… - Frontiers in …, 2022 - frontiersin.org
As an anti-inflammatory alkaloid, nicotine plays dual roles in treating diseases. Here we
reviewed the anti-inflammatory and pro-inflammatory effects of nicotine on inflammatory …

[HTML][HTML] Impact of gastrointestinal physiology on drug absorption in special populations––An UNGAP review

C Stillhart, K Vučićević, P Augustijns, AW Basit… - European Journal of …, 2020 - Elsevier
The release and absorption profile of an oral medication is influenced by the
physicochemical properties of the drug and its formulation, as well as by the anatomy and …

Programmable probiotics modulate inflammation and gut microbiota for inflammatory bowel disease treatment after effective oral delivery

J Zhou, M Li, Q Chen, X Li, L Chen, Z Dong… - Nature …, 2022 - nature.com
Reactive oxygen species (ROS) play vital roles in intestinal inflammation. Therefore,
eliminating ROS in the inflammatory site by antioxidant enzymes such as catalase and …

Chemistry, pharmacokinetics, pharmacological activities, and toxicity of Quercitrin

J Chen, G Li, C Sun, F Peng, L Yu, Y Chen… - Phytotherapy …, 2022 - Wiley Online Library
Quercitrin is a naturally available type of flavonoid that commonly functions as the dietary
ingredient and supplement. So far, a wide spectrum of bioactivities of quercitrin have been …

[HTML][HTML] Gut microbiota in various childhood disorders: Implication and indications

NK Saeed, M Al-Beltagi, AS Bediwy… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Gut microbiota has a significant role in gut development, maturation, and immune system
differentiation. It exerts considerable effects on the child's physical and mental development …

[HTML][HTML] Stress triggers flare of inflammatory bowel disease in children and adults

Y Sun, L Li, R Xie, B Wang, K Jiang, H Cao - Frontiers in pediatrics, 2019 - frontiersin.org
Inflammatory bowel disease (IBD) is an idiopathic inflammatory disease characterized by
chronic and relapsing manifestations. It is noteworthy that the prevalence of IBD is gradually …

An update on inflammatory bowel disease

T Sairenji, KL Collins, DV Evans - Primary Care: Clinics …, 2017 - primarycare.theclinics.com
An Update on Inflammatory Bowel Disease - Primary Care: Clinics in Office Practice Skip to
Main Content Advertisement Primary Care: Clinics in Office Practice Log in Register Log in …

[PDF][PDF] Mucosal profiling of pediatric-onset colitis and IBD reveals common pathogenics and therapeutic pathways

B Huang, Z Chen, L Geng, J Wang, H Liang, Y Cao… - Cell, 2019 - cell.com
Pediatric-onset colitis and inflammatory bowel disease (IBD) have significant effects on the
growth of infants and children, but the etiopathogenesis underlying disease subtypes …

[HTML][HTML] Natural anti-inflammatory compounds as drug candidates for inflammatory bowel disease

L Duan, S Cheng, L Li, Y Liu, D Wang… - Frontiers in …, 2021 - frontiersin.org
Inflammatory bowel disease (IBD) represents chronic recurrent intestinal inflammation
resulting from various factors. Crohn's disease (CD) and ulcerative colitis (UC) have been …

[HTML][HTML] Tiliroside ameliorates ulcerative colitis by restoring the M1/M2 macrophage balance via the HIF-1α/glycolysis pathway

H Zhuang, Q Lv, C Zhong, Y Cui, L He… - Frontiers in …, 2021 - frontiersin.org
Macrophages polarized to different phenotypes critically contribute to colitis development by
coordinating inflammatory and anti-inflammatory processes. Herein, targeting the balance …