Alzheimer's disease and its treatment by different approaches: A review

S Srivastava, R Ahmad, SK Khare - European Journal of Medicinal …, 2021 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder that impairs mental ability
development and interrupts neurocognitive function. This neuropathological condition is …

Mitochondria and lipid peroxidation in the mechanism of neurodegeneration: Finding ways for prevention

PR Angelova, N Esteras… - Medicinal Research …, 2021 - Wiley Online Library
The world's population aging progression renders age‐related neurodegenerative diseases
to be one of the biggest unsolved problems of modern society. Despite the progress in …

[HTML][HTML] Neuroprotective natural products for Alzheimer's disease

X Chen, J Drew, W Berney, W Lei - Cells, 2021 - mdpi.com
Alzheimer's disease (AD) is the number one neurovegetative disease, but its treatment
options are relatively few and ineffective. In efforts to discover new strategies for AD therapy …

[HTML][HTML] Solid lipid nanoparticles (SLNs): an advanced drug delivery system targeting brain through BBB

MK Satapathy, TL Yen, JS Jan, RD Tang, JY Wang… - Pharmaceutics, 2021 - mdpi.com
The blood–brain barrier (BBB) plays a vital role in the protection and maintenance of
homeostasis in the brain. In this way, it is an interesting target as an interface for various …

[HTML][HTML] Dietary polyphenols—Important non-nutrients in the prevention of chronic noncommunicable diseases. A systematic review

W Koch - Nutrients, 2019 - mdpi.com
The improvement of the social and economic conditions of society has eliminated the threat
of death from the majority of infectious diseases. However, the rapid progress of civilization …

[HTML][HTML] Bioavailability of tea catechins and its improvement

ZY Cai, XM Li, JP Liang, LP Xiang, KR Wang, YL Shi… - Molecules, 2018 - mdpi.com
Many in vitro studies have shown that tea catechins had vevarious health beneficial effects.
However, inconsistent results between in vitro and in vivo studies or between laboratory …

Therapeutics of Alzheimer's disease: Past, present and future

R Anand, KD Gill, AA Mahdi - Neuropharmacology, 2014 - Elsevier
Alzheimer's disease (AD) is the most common cause of dementia worldwide. The etiology is
multifactorial, and pathophysiology of the disease is complex. Data indicate an exponential …

Multifaceted role of phyto-derived polyphenols in nanodrug delivery systems

Z Chen, MA Farag, Z Zhong, C Zhang, Y Yang… - Advanced drug delivery …, 2021 - Elsevier
As naturally occurring bioactive products, several lines of evidence have shown the potential
of polyphenols in the medical intervention of various diseases, including tumors …

[HTML][HTML] Encapsulation of natural polyphenolic compounds; a review

A Munin, F Edwards-Lévy - Pharmaceutics, 2011 - mdpi.com
Natural polyphenols are valuable compounds possessing scavenging properties towards
radical oxygen species, and complexing properties towards proteins. These abilities make …

[HTML][HTML] Bioavailability enhancement of EGCG by structural modification and nano-delivery: A review

W Dai, C Ruan, Y Zhang, J Wang, J Han, Z Shao… - Journal of Functional …, 2020 - Elsevier
EGCG is an important bioactive component of green tea, which has the biological functions
of antioxidant and antitumor. However, the stability of EGCG is poor, the absorption rate is …