Redox reactions are intrinsically linked to energy metabolism. Therefore, redox processes
are indispensable for organismal physiology and life itself. The term reactive oxygen species …

Reactive oxygen species (ROS) play important roles in tissue homeostasis, cellular
signaling, differentiation, and survival. In this review, we discuss the types of ROS, their …

In the open metabolic system, redox-related signaling requires continuous monitoring and
fine-tuning of the steady-state redox set point. The ongoing oxidative metabolism is a …

The sulfur biochemistry of the thiol group endows cysteines with a number of highly
specialized and unique features that enable them to serve a variety of different functions in …

The concept of cell signaling in the context of nonenzyme-assisted protein modifications by
reactive electrophilic and oxidative species, broadly known as redox signaling, is a uniquely …

Metabolites affect cell growth in two different ways. First, they serve as building blocks for
biomass accumulation. Second, metabolites regulate the activity of growth-relevant …

Post-translational modifications (PTMs) provide a rapid response to stimuli, finely tuning
metabolism and gene expression and maintain homeostasis. Advances in mass …

The importance of coenzyme A (CoA) as a carrier of acyl residues in cell metabolism is well
understood. Coenzyme A participates in more than 100 different catabolic and anabolic …

Coenzyme A (CoA) is the predominant acyl carrier in mammalian cells and a cofactor that
plays a key role in energy and lipid metabolism. CoA and its thioesters (acyl-CoAs) regulate …

In a diverse family of cellular cofactors, coenzyme A (CoA) has a unique design to function in
various biochemical processes. The presence of a highly reactive thiol group and a …