Cytokines are critical in regulating immune responses and cellular behavior, playing dual
roles in both normal physiology and the pathology of diseases such as cancer. These …

In the field of breast cancer treatment, the immunotherapy involving natural killer (NK) cells
is increasingly highlighting its distinct potential and significance. Members of the interleukin …

Improving clinical immunotherapy for glioblastoma (GBM) relies on addressing the
immunosuppressive tumor microenvironment (TME). Enhancing CD8+ T cell infiltration and …

Intratumoral regulatory T cells (Tregs) are key mediators of cancer immunotherapy
resistance, including anti-PD-(L) 1 immune checkpoint blockade (ICB). The mechanisms …

IL2 signals pleiotropically on diverse cell types, some of which contribute to therapeutic
activity against tumors, whereas others drive undesired activity, such as immunosuppression …

再生障碍性贫血(aplastic anemia, AA) 是一组以造血干细胞损伤, 骨髓脂肪化,
外周血全血细胞减少为特征的骨髓造血功能衰竭性疾病. 中国中医科学院西苑医院血液科一直 …

Various combination therapies have been investigated to overcome the limitations of using
immune checkpoint inhibitors. However, determining the optimal combination therapy …

The balance of the microbiome, which is sensitive to temperature changes, plays a crucial
role in maintaining overall health and reducing the risk of diseases. However, the specific …

Children living with HIV have a higher risk of developing tuberculosis (TB), a disease
caused by the bacterium Mycobacterium tuberculosis (Mtb). Gamma delta (γδ) T cells in the …

Background DARS2 is a pivotal member of the Aminoacyl-tRNA synthetases family that is
critical for regulating protein translation. However, the biological role of DARS2 in bladder …