The essential role of the gut microbiota for health has generated tremendous interest in
modulating its composition and metabolic function. One of these strategies is prebiotics …

The epidermis contains epithelial cells, immune cells, and microbes which provides a
physical and functional barrier to the protection of human skin. It plays critical roles in …

Atopic dermatitis (AD) is the most common inflammatory skin disease in the industrialized
world and has multiple causes. Over the past decade, data from both experimental models …

Background: Cutibacterium acnes has been identified as one of the main triggers of acne.
However, increasing knowledge of the human skin microbiome raises questions about the …

It is well established that adaptive immune responses are deficient in early life, contributing
to increased mortality and morbidity. The developmental trajectories of different components …

Atopic dermatitis (AD) is a common chronic skin inflammatory disorder characterized by
recurrent eczema accompanied by an intractable itch that leads to an impaired quality of life …

The skin is the largest human organ. It has three layers: the epidermis, the dermis, and the
hypodermis. The epidermis is the outer layer, formed by a stratified, squamous epithelium …

Background Patients with atopic dermatitis (AD) are prone to skin infections, with microbes
such as Staphylococcus aureus suspected of contributing to pathogenesis. Bleach baths …

Skin barrier abnormalities have been suggested to play an essential role in initiation of early
atopic dermatitis (AD). Antigen penetration through a compromised barrier likely leads to …

Regulatory T-cells (Tregs) act at the interface of host and pathogen interactions in human
infectious diseases. Tregs are induced by a wide range of pathogens, but distinct effects of …