The primary objective of this study was to systematically review and analyse epidemiological
studies of the prevalence and incidence of atopic dermatitis (AD) during childhood and …

The global epidemiology of atopic dermatitis (AD) in the current decade (2009–2019) has
not been extensively reported. Epidemiological studies play an important role in presenting …

Summary Background The Global Burden of Disease (GBD) Study provides an annually
updated resource to study disease‐related morbidity and mortality worldwide. Objectives …

Sulfoximines have been largely disregarded in medicinal chemistry for a long time.
However, recently, they have risen to the apparent level of stardom on the drug discovery …

Population-based estimates on the prevalence of atopic dermatitis in adults vary widely. The
objectives of this study were to determine the prevalence of atopic dermatitis in the …

Objective To provide an overview of filaggrin biology and the role of filaggrin variants in
atopic dermatitis (AD) and allergic disease. Data Sources We performed a PubMed literature …

Atopic dermatitis (AD), the most common chronic inflammatory skin disease, is driven by
both terminal keratinocyte differentiation defects and strong type 2 immune responses. In …

The discovery in 2006 that loss-of-function mutations in the filaggrin gene (FLG) cause
ichthyosis vulgaris and can predispose to atopic dermatitis (AD) galvanized the dermatology …

Background Despite unmet need, 15 years have passed since a topical therapy with a new
mechanism of action for atopic dermatitis (AD) has been approved. Janus kinase (JAK) …

Background Atopic dermatitis (AD) shows very high prevalence in Asia, with a large unmet
need for effective therapeutics. Direct comparisons between European American (EA) and …