Intestinal diseases, such as inflammatory bowel diseases (IBDs) and colorectal cancer
(CRC) generally characterized by clinical symptoms, including malabsorption, intestinal …

Ischemia‐reperfusion injury (IRI) refers to a syndrome in which tissue damage is further
aggravated and organ function further deteriorates when blood flow is restored after a period …

Cutaneous wounds are among the most common soft tissue injuries and are particularly
hard to heal in aging. Caloric restriction (CR) is well documented to extend longevity; …

Macroautophagy/autophagy is an evolutionally conserved catabolic process in which
cytosolic contents, such as aggregated proteins, dysfunctional organelle, or invading …

Dietary fibre, such as indigestible oligosaccharides and polysaccharides, occurs in many
foods and has gained considerable importance related to its beneficial effects on host health …

Metformin is currently the most prescribed drug for treatment of type 2 diabetes mellitus in
humans. It has been well established that long-term treatment with metformin improves …

The gut mucosa of human is covered by mucus, functioning as a crucial defense line for the
intestine against external stimuli and pathogens. Mucin2 (MUC2) is a subtype of secretory …

The aim of this study is to investigate the effect of chitosan oligosaccharides (COS) on type 2
diabetes mellitus. Wild type C57BL/6J mice or diabetic db/db mice were treated with vehicle …

Disruption of the gut barrier results in severe clinical outcomes with no specific treatment.
Metabolic disorders and destruction of enterocytes play key roles in gut barrier dysfunction …

Akkermansia muciniphila is well known for the amelioration of inflammatory responses and
restoration of intestinal barrier function. The beneficial effect of A. muciniphila occurred …