Programmed genome rearrangements in ciliates
I Rzeszutek, XX Maurer-Alcalá, M Nowacki - Cellular and Molecular Life …, 2020 - Springer
Ciliates are a highly divergent group of unicellular eukaryotes with separate somatic and
germline genomes found in distinct dimorphic nuclei. This characteristic feature is tightly …
germline genomes found in distinct dimorphic nuclei. This characteristic feature is tightly …
Programmed Rearrangement in Ciliates: Paramecium
M Betermier, S Duharcourt - Mobile DNA III, 2015 - Wiley Online Library
Ciliates belong to a monophyletic group of unicellular eukaryotes within the Alveolate
branch (1). The species that have been used as model organisms are free‐living organisms …
branch (1). The species that have been used as model organisms are free‐living organisms …
Structure of the germline genome of Tetrahymena thermophila and relationship to the massively rearranged somatic genome
EP Hamilton, A Kapusta, PE Huvos, SL Bidwell, N Zafar… - elife, 2016 - elifesciences.org
The germline genome of the binucleated ciliate Tetrahymena thermophila undergoes
programmed chromosome breakage and massive DNA elimination to generate the somatic …
programmed chromosome breakage and massive DNA elimination to generate the somatic …
Genome-defence small RNAs exapted for epigenetic mating-type inheritance
DP Singh, B Saudemont, G Guglielmi, O Arnaiz… - Nature, 2014 - nature.com
In the ciliate Paramecium, transposable elements and their single-copy remnants are
deleted during the development of somatic macronuclei from germline micronuclei, at each …
deleted during the development of somatic macronuclei from germline micronuclei, at each …
The compact macronuclear genome of the ciliate Halteria grandinella: a transcriptome-like genome with 23,000 nanochromosomes
How to achieve protein diversity by genome and transcriptome processing is essential for
organismal complexity and adaptation. The present work identifies that the macronuclear …
organismal complexity and adaptation. The present work identifies that the macronuclear …
Genome-wide analysis of genetic and epigenetic control of programmed DNA deletion
EC Swart, CD Wilkes, PY Sandoval… - Nucleic Acids …, 2014 - academic.oup.com
During the development of the somatic genome from the Paramecium germline genome the
bulk of the copies of∼ 45 000 unique, internal eliminated sequences (IESs) are deleted. IES …
bulk of the copies of∼ 45 000 unique, internal eliminated sequences (IESs) are deleted. IES …
Ciliate research: From myth to trendsetting science
H Plattner - Journal of Eukaryotic Microbiology, 2022 - Wiley Online Library
This special issue of the Journal of Eukaryotic Microbiology (JEM) summarizes
achievements obtained by generations of researchers with ciliates in widely different …
achievements obtained by generations of researchers with ciliates in widely different …
Environmentally induced plasticity of programmed DNA elimination boosts somatic variability in Paramecium tetraurelia
Can ecological changes impact somatic genome development? Efforts to resolve this
question could reveal a direct link between environmental changes and somatic variability …
question could reveal a direct link between environmental changes and somatic variability …
One Cell, Two Gears: Extensive Somatic Genome Plasticity Accompanies High Germline Genome Stability in Paramecium
Mutation accumulation (MA) experiments are conventionally employed to study
spontaneous germline mutations. However, MA experiments can also shed light on somatic …
spontaneous germline mutations. However, MA experiments can also shed light on somatic …
Cross-Generational Effects and Non-random Developmental Response to Temperature Variation in Paramecium
Unicellular organisms such as ciliates are largely neglected in research on adaptive
developmental plasticity, although their nuclear dualism offers ideal circumstances to study …
developmental plasticity, although their nuclear dualism offers ideal circumstances to study …