Amyotrophic lateral sclerosis (ALS) is a complex neurodegenerative disease that is
classically thought to impact the motor system. Over the past 20 years, research has started …

Neurogenic atrophy refers to the loss of muscle mass and function that results directly from
injury or disease of the peripheral nervous system. Individuals with neurogenic atrophy may …

Background The survival time of amyotrophic lateral sclerosis (ALS) is greatly variable and
protective or risk effects of the potential survival predictors are controversial. Thus, we aim to …

Objective To identify dysregulated metabolic pathways in amyotrophic lateral sclerosis (ALS)
versus control participants through untargeted metabolomics. Methods Untargeted …

Objective To determine the prevalence and prognostic value of weight loss (WL) prior to
diagnosis in patients with amyotrophic lateral sclerosis (ALS). Methods We enrolled patients …

Amyotrophic lateral sclerosis (ALS) displays considerable clinical and genetic
heterogeneity. Machine learning approaches have previously been utilised for patient …

Neurogenic muscle atrophy is the loss of skeletal muscle mass and function that occurs with
nerve injury and in denervating diseases, such as amyotrophic lateral sclerosis. Aside from …

Amyotrophic lateral sclerosis (ALS) is a serious neurodegenerative disease that affects
motor neurons and leads to death within 2 to 3 years after the first symptoms manifest …

Background Malnutrition and weight loss are negative prognostic factors for survival in
patients with amyotrophic lateral sclerosis (ALS). However, energy expenditure at rest (REE) …

Introduction Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease
with loss of muscle function. The pathogenesis is still unclear and the heterogeneity of ALS …