Huntington disease (HD) is a neurodegenerative disease caused by CAG repeat expansion
in the huntingtin gene (HTT) and involves a complex web of pathogenic mechanisms …

Self-assembly has emerged as an extensively used method for constructing biomaterials
with sizes ranging from nanometers to micrometers. Peptides have been extensively …

Mitochondrial dysfunction is a central aspect of aging and neurodegenerative diseases,
including Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and …

Huntington's disease is a progressive, fatal, neurodegenerative disorder caused by an
expanded CAG repeat in the huntingtin gene, which encodes an abnormally long …

Huntington's disease (HD) is an incurable neurodegenerative disease characterized by
abnormal motor movements, personality changes, and early death. HD is caused by a …

Machado–Joseph disease (MJD), also known as spinocerebellar ataxia type 3 (SCA3), is
the most common inherited spinocerebellar ataxia and one of many polyglutamine …

For many years, oxidative thiol modifications in cytosolic proteins were largely disregarded
as in vitro artifacts, and considered unlikely to play significant roles within the reducing …

Huntington's disease (HD) is the most common inherited neurodegenerative disease and is
characterized by uncontrolled excessive motor movements and cognitive and emotional …

Polyglutamine diseases are a major cause of neurodegeneration worldwide. Recent studies
highlight the importance of protein quality control mechanisms in regulating polyglutamine …

Huntington's disease is a genetic neurodegenerative disorder resulting from polyglutamine
(polyQ) expansion (> 36Q) within the first exon of Huntingtin (Htt) protein. We applied X-ray …