Neuroprotective mechanisms of resveratrol in Alzheimer's disease: role of SIRT1

BAQ Gomes, JPB Silva, CFR Romeiro… - Oxidative medicine …, 2018 - Wiley Online Library
Alzheimer's disease (AD) is a progressive and neurodegenerative disorder of the cortex and
hippocampus, which eventually leads to cognitive impairment. Although the etiology of AD …

Health benefits and phenolic compounds of Moringa oleifera leaves: A comprehensive review

MA Hassan, T Xu, Y Tian, Y Zhong, FAZ Ali, X Yang… - Phytomedicine, 2021 - Elsevier
Abstract Background Moringa oleifera Lam (MO) is native to India and is a cash crop widely
cultivated in tropical and sub-tropical areas. The health improving properties of MO has …

Resveratrol for Alzheimer's disease

C Sawda, C Moussa, RS Turner - … of the New York Academy of …, 2017 - Wiley Online Library
The amyloid hypothesis suggests that the progressive accumulation and deposition of
central nervous system (CNS) amyloid with aging is the proximate cause of Alzheimer's …

Current evidence on the effect of dietary polyphenols intake on chronic diseases

C Costa, A Tsatsakis, C Mamoulakis, M Teodoro… - Food and Chemical …, 2017 - Elsevier
Polyphenols are secondary metabolites of plants. They comprise several antioxidant
compounds and they are generally considered to be involved in the defense against human …

Inhibitors of NF-κB and P2X7/NLRP3/Caspase 1 pathway in microglia: Novel therapeutic opportunities in neuroinflammation induced early-stage Alzheimer's disease

BS Thawkar, G Kaur - Journal of neuroimmunology, 2019 - Elsevier
Microglial activation is a distinguished attribute in many neurodegenerative diseases of
aging. Compelling evidence suggests that neuroinflammation stimulated by microglia, the …

The mechanisms of action of curcumin in Alzheimer's disease

M Tang, C Taghibiglou - Journal of Alzheimer's disease, 2017 - content.iospress.com
Alzheimer's disease (AD) is a neurodegenerative disorder of the elderly. As the prevalence
of AD rises in the 21st century, there is an urgent need for the development of effective …

Targeting neuroinflammation in Alzheimer's disease

MR Bronzuoli, A Iacomino, L Steardo… - Journal of inflammation …, 2016 - Taylor & Francis
Almost 47 million people suffer from dementia worldwide, with an estimated new case
diagnosed every 3.2 seconds. Alzheimer's disease (AD) accounts for approximately 60 …

Oxidative stress, inflammation, and neuroprogression in chronic PTSD

MW Miller, AP Lin, EJ Wolf… - Harvard review of …, 2018 - journals.lww.com
Posttraumatic stress disorder is a serious and often disabling syndrome that develops in
response to a traumatic event. Many individuals who initially develop the disorder go on to …

Resveratrol and brain mitochondria: a review

FR Jardim, FT de Rossi, MX Nascimento… - Molecular …, 2018 - Springer
Abstract Resveratrol (3, 4', 5-trihydroxystilbene; C 14 H 12 O 3) is a polyphenolic phytoalexin
found in grapes, berries, peanuts, and wines. Resveratrol has been viewed as an …

Apigenin as neuroprotective agent: Of mice and men

SF Nabavi, H Khan, G D'onofrio, D Šamec… - Pharmacological …, 2018 - Elsevier
Neurodegenerative disorders (NDDs) such as Alzheimer's and Parkinson's diseases are the
most common age-related pathologies that affect millions of people all over the world. To …