Tick-borne encephalitis (TBE) is an illness caused by tick-borne encephalitis virus (TBEV)
infection which is often limited to a febrile illness, but may lead to very aggressive …

The chemistry of heterocyclic compounds has traditionally been and remains a bright area of
chemical science in Russia. This is due to the fact that many heterocycles find the widest …

A series of new hybrid molecules containing 2-furyl and partially saturated pyridine
fragments was obtained based on the reaction of cyanothioacetamide with furfural and 1, 3 …

Tick-borne encephalitis (TBE) is a potentially fatal disease common in much of Europe and
Asia. There is no specific therapy for the treatment of TBE patients. However, several efforts …

Spirocyclic compounds containing heterocyclic moieties represent promising 3D scaffolds
for modern drug design. In the search for novel anti-flaviviral agents, we have obtained a …

Humic substances (HS) are complex natural mixtures comprising a large variety of
compounds produced during decomposition of decaying biomass. The molecular …

Infections caused by flaviviruses pose a huge threat for public health all over the world. The
search for therapeutically relevant compounds targeting tick-borne flaviviruses requires the …

Rigid amphipathic fusion inhibitors (RAFIs) are potent antivirals based on a perylene core
linked with a nucleoside moiety. Sugar-free analogues of RAFIs, 5-(perylen-3-ylethynyl) …

Tick-borne encephalitis (TBE) is an infectious disease common for Northern Eurasia and
caused by the tick-borne encephalitis virus (TBEV) from the Flavivirus genus. Usually, TBEV …

A series of new hybrid molecules containing fragments of anestesin and 4-(2-furyl)-1, 4-
dihydronicotinonitrile have been obtained starting from diketene, ethyl 4-aminobenzoate …