Native fluorescence, or autofluorescence (AF), consists in the emission of light in the UV-
visible, near-IR spectral range when biological substrates are excited with light at suitable …

Mitochondria play a pivotal role in energy metabolism, programmed cell death and oxidative
stress. Mutated mitochondrial DNA in diseased cells compromises the structure of key …

Much of the mechanism by which Wnt signaling drives proliferation during oncogenesis is
attributed to its regulation of the cell cycle. Here, we show how Wnt/β‐catenin signaling …

Chemotherapy for hepatoblastoma is limited by organ toxicity and poor outcomes, prompting
the search for new, more effective treatments with minimal side effects. Vincristine sulfate, a …

Autofluorescence emission of liver tissue depends on the presence of endogenous
biomolecules able to fluoresce under suitable light excitation. Overall autofluorescence …

Acute liver failure, the fatal deterioration of liver function, is the most common indication for
emergency liver transplantation, and drug-induced liver injury and viral hepatitis are …

Resveratrol is a well known polyphenol largely produced in grapevine. It is a strong
antioxidant and a free radical scavenger. It exhibits several beneficial effects for health …

Polyploid cells show great among-species and among-tissues diversity and relation to
developmental mode, suggesting their importance in adaptive evolution and developmental …

Background: EGF-induced activation of mTORC1 in hepatocytes is essential for cell
proliferation. Results: Blocking EGF-induced vacuolar acidification reduced intracellular …

A time-resolved spectroscopic imaging system is built to study the fluorescence
characteristics of nicotinamide adenine dinucleotide (NADH), an important metabolic …