Reward mechanisms in obesity: new insights and future directions

PJ Kenny - Neuron, 2011 - cell.com
Food is consumed in order to maintain energy balance at homeostatic levels. In addition,
palatable food is also consumed for its hedonic properties independent of energy status …

Common cellular and molecular mechanisms in obesity and drug addiction

PJ Kenny - Nature Reviews Neuroscience, 2011 - nature.com
The hedonic properties of food can stimulate feeding behaviour even when energy
requirements have been met, contributing to weight gain and obesity. Similarly, the hedonic …

Associations between age discrimination and health and wellbeing: cross-sectional and prospective analysis of the English Longitudinal Study of Ageing

SE Jackson, RA Hackett, A Steptoe - The Lancet Public Health, 2019 - thelancet.com
Background Age discrimination (or ageism) is pervasive in society. Other forms of
discrimination (such as racism) have been linked with adverse health outcomes, but age …

Apo-ghrelin receptor forms heteromers with DRD2 in hypothalamic neurons and is essential for anorexigenic effects of DRD2 agonism

A Kern, R Albarran-Zeckler, HE Walsh, RG Smith - Neuron, 2012 - cell.com
We identified subsets of neurons in the brain that coexpress the dopamine receptor subtype-
2 (DRD2) and the ghrelin receptor (GHSR1a). Combination of FRET confocal microscopy …

Perceived weight discrimination and changes in weight, waist circumference, and weight status

SE Jackson, RJ Beeken, J Wardle - Obesity, 2014 - Wiley Online Library
Objective To examine associations between perceived weight discrimination and changes
in weight, waist circumference, and weight status. Methods Data were from 2944 men and …

Maternal high fat diet consumption during the perinatal period programs offspring behavior

EL Sullivan, EK Nousen, KA Chamlou - Physiology & behavior, 2014 - Elsevier
The environment that a developing offspring experiences during the perinatal period is
markedly influenced by maternal health and diet composition. Evidence from both …

Biological control of appetite: a daunting complexity

PS MacLean, JE Blundell, JA Mennella… - Obesity, 2017 - Wiley Online Library
Objective This review summarizes a portion of the discussions of an NIH Workshop
(Bethesda, MD, 2015) titled “Self‐Regulation of Appetite—It's Complicated,” which focused …

Hedonic and incentive signals for body weight control

E Egecioglu, KP Skibicka, C Hansson… - Reviews in Endocrine …, 2011 - Springer
Here we review the emerging neurobiological understanding of the role of the brain's reward
system in the regulation of body weight in health and in disease. Common obesity is …

Dopaminergic modulation of sucrose acceptance behavior in Drosophila

S Marella, K Mann, K Scott - Neuron, 2012 - cell.com
For an animal to survive in a constantly changing environment, its behavior must be shaped
by the complex milieu of sensory stimuli it detects, its previous experience, and its internal …

Children's health in the digital age

B Dresp-Langley - International journal of environmental research and …, 2020 - mdpi.com
Environmental studies, metabolic research, and state of the art research in neurobiology
point towards the reduced amount of natural day and sunlight exposure of the developing …