Soluble tumor necrosis factor alpha promotes retinal ganglion cell death in glaucoma via calcium-permeable AMPA receptor activation

JLC Vargas, IK Osswald, N Unsain… - Journal of …, 2015 - Soc Neuroscience
Loss of vision in glaucoma results from the selective death of retinal ganglion cells (RGCs).
Tumor necrosis factor α (TNFα) signaling has been linked to RGC damage, however, the …

Cytotoxicity of cobalt chloride in brain cell lines-a comparison between astrocytoma and neuroblastoma cells

S Gómez-Arnaiz, RJ Tate, MH Grant - Toxicology in vitro, 2020 - Elsevier
High levels of circulating cobalt ions in blood have been reported to induce systemic
reactions in patients with metal-on-metal (MoM) hip implants. We still lack information …

Calcium-permeable AMPA receptors on AII amacrine cells mediate sustained signaling in the On-pathway of the primate retina

KA Percival, J Gayet, R Khanjian, WR Taylor… - Cell reports, 2022 - cell.com
Midget and parasol ganglion cells (GCs) represent the major output channels from the
primate eye to the brain. On-type midget and parasol GCs exhibit a higher background spike …

Evidence of calcium-permeable AMPA receptors in dendritic spines of CA1 pyramidal neurons

HA Mattison, AA Bagal… - Journal of …, 2014 - journals.physiology.org
GluA2-lacking, calcium-permeable α-amino-3-hydroxy-5-methylisoxazole-4-propionate
receptors (AMPARs) have unique properties, but their presence at excitatory synapses in …

Cobalt toxicity mechanisms in neural cells and brain tissue: understanding the implications for patients with cobalt-chromium alloy orthopaedic implants

S Gomez-Arnaiz - 2022 - stax.strath.ac.uk
The most recent regulatory update on metal-on-metal (MoM) hip replacements
(MDA/2017/018, 2017) has resulted in the monitoring of cobalt and chromium levels in circa …