Chemical strategies to engineer hydrogels for cell culture

J Lou, DJ Mooney - Nature Reviews Chemistry, 2022 - nature.com
Two-dimensional and three-dimensional cell culture systems are widely used for biological
studies, and are the basis of the organoid, tissue engineering and organ-on-chip research …

Engineered hydrogels for mechanobiology

U Blache, EM Ford, B Ha, L Rijns… - Nature Reviews …, 2022 - nature.com
Cells' local mechanical environment can be as important in guiding cellular responses as
many well-characterized biochemical cues. Hydrogels that mimic the native extracellular …

[HTML][HTML] Skin-like mechanoresponsive self-healing ionic elastomer from supramolecular zwitterionic network

W Zhang, B Wu, S Sun, P Wu - Nature Communications, 2021 - nature.com
Stretchable ionic skins are intriguing in mimicking the versatile sensations of natural skins.
However, for their applications in advanced electronics, good elastic recovery, self-healing …

Covalent organic frameworks: design, synthesis, and functions

K Geng, T He, R Liu, S Dalapati, KT Tan, Z Li… - Chemical …, 2020 - ACS Publications
Covalent organic frameworks (COFs) are a class of crystalline porous organic polymers with
permanent porosity and highly ordered structures. Unlike other polymers, a significant …

The stiffness of living tissues and its implications for tissue engineering

CF Guimarães, L Gasperini, AP Marques… - Nature Reviews …, 2020 - nature.com
The past 20 years have witnessed ever-growing evidence that the mechanical properties of
biological tissues, from nanoscale to macroscale dimensions, are fundamental for cellular …

Soft bioelectronics based on nanomaterials

KW Cho, SH Sunwoo, YJ Hong, JH Koo… - Chemical …, 2021 - ACS Publications
Recent advances in nanostructured materials and unconventional device designs have
transformed the bioelectronics from a rigid and bulky form into a soft and ultrathin form and …

3D extracellular matrix mimics: fundamental concepts and role of materials chemistry to influence stem cell fate

J Nicolas, S Magli, L Rabbachin, S Sampaolesi… - …, 2020 - ACS Publications
Synthetic 3D extracellular matrices (ECMs) find application in cell studies, regenerative
medicine, and drug discovery. While cells cultured in a monolayer may exhibit unnatural …

Hydrogel scaffolds for tissue engineering: the importance of polymer choice

CD Spicer - Polymer Chemistry, 2020 - pubs.rsc.org
Hydrogel scaffolds that can repair or regrow damaged biological tissue have great potential
for the treatment of injury and disease. These biomaterials are widely used in the tissue …

Alkyne-palladium (II)-catalyzed living polymerization of isocyanides: an exploration of diverse structures and functions

N Liu, L Zhou, ZQ Wu - Accounts of Chemical Research, 2021 - ACS Publications
Conspectus Inspired by the perfect helical structures and the resulting exquisite functions of
biomacromolecules, helical polymers have attracted increasing attention in recent years …

Design principles of food gels

Y Cao, R Mezzenga - Nature Food, 2020 - nature.com
Naturally sourced gels from food biopolymers have advanced in recent decades to compare
favourably in performance and breadth of application to their synthetic counterparts. Here …