Orphan GPR52 as an emerging neurotherapeutic target
GPR52 is a highly conserved, brain-enriched, G s/olf-coupled orphan G protein-coupled
receptor (GPCR) that controls various cyclic AMP (cAMP)-dependent physiological and …
receptor (GPCR) that controls various cyclic AMP (cAMP)-dependent physiological and …
[HTML][HTML] Application of FRET-and BRET-based live-cell biosensors in deorphanization and ligand discovery studies on orphan G protein-coupled receptors
JJ Sajkowska, CH Tsang, P Kozielewicz - SLAS Discovery, 2024 - Elsevier
Bioluminescence-and fluorescence-based resonance energy transfer assays have gained
considerable attention in pharmacological research as high-throughput scalable tools …
considerable attention in pharmacological research as high-throughput scalable tools …
The Orphan G Protein-Coupled Receptor GPR52 is a Novel Regulator of Breast Cancer Multicellular Organization
SZ Hanif, CMC Au, I Torregroza, SY Jannath… - …, 2024 - pmc.ncbi.nlm.nih.gov
G protein-coupled receptors (GPCRs) are the largest class of membrane-bound receptors
and transmit critical signals from the extracellular to the intracellular spaces. Transcriptomic …
and transmit critical signals from the extracellular to the intracellular spaces. Transcriptomic …