Mitochondria and lipid peroxidation in the mechanism of neurodegeneration: Finding ways for prevention

PR Angelova, N Esteras… - Medicinal Research …, 2021 - Wiley Online Library
The world's population aging progression renders age‐related neurodegenerative diseases
to be one of the biggest unsolved problems of modern society. Despite the progress in …

[HTML][HTML] Antioxidant and Anti-Inflammatory Effects of Citrus Flavonoid Hesperetin: Special Focus on Neurological Disorders

A Khan, M Ikram, JR Hahm, MO Kim - Antioxidants, 2020 - mdpi.com
Neurodegenerative disorders have emerged as a serious health issue in the current era.
The most common neurodegenerative disorders are Alzheimer's disease (AD), Parkinson's …

[HTML][HTML] Cadmium-induced oxidative stress: focus on the central nervous system

JJV Branca, C Fiorillo, D Carrino, F Paternostro… - Antioxidants, 2020 - mdpi.com
Cadmium (Cd), a category I human carcinogen, is a well-known widespread environmental
pollutant. Chronic Cd exposure affects different organs and tissues, such as the central …

Role of heavy metals (copper (Cu), arsenic (As), cadmium (Cd), iron (Fe) and lithium (Li)) induced neurotoxicity

B Vellingiri, A Suriyanarayanan, P Selvaraj… - Chemosphere, 2022 - Elsevier
Parkinson's disease (PD) is a neurodegenerative condition characterized by the dopamine
(DA) neuronal loss in the substantia nigra. PD impairs motor controls symptoms such as …

[HTML][HTML] Neurological enhancement effects of melatonin against brain injury-induced oxidative stress, neuroinflammation, and neurodegeneration via AMPK/CREB …

SU Rehman, M Ikram, N Ullah, SI Alam, HY Park… - Cells, 2019 - mdpi.com
Oxidative stress and energy imbalance strongly correlate in neurodegenerative diseases.
Repeated concussion is becoming a serious public health issue with uncontrollable adverse …

Protocatechuic acid mitigates cadmium-induced neurotoxicity in rats: Role of oxidative stress, inflammation and apoptosis

EM Al Olayan, AS Aloufi, OD AlAmri, H Ola… - Science of the total …, 2020 - Elsevier
Environmental and occupational exposure to heavy metals, including cadmium (Cd), is
associated with extremely adverse impacts to living systems. Antioxidant agents are …

Beneficial effects of Chrysin on Cadmium‐induced nephrotoxicity in rats: Modulating the levels of Nrf2/HO‐1, RAGE/NLRP3, and Caspase-3/Bax/Bcl-2 signaling …

H Şimşek, N Akaras, C Gür, S Küçükler, FM Kandemir - Gene, 2023 - Elsevier
Cadmium (Cd) is a toxic heavy metal that targets the kidney directly in the body. Chrysin
(CHR) is a natural flavonoid with many properties such as antioxidant, anti-inflammatory and …

[HTML][HTML] Antioxidant and neuroprotective effects of caffeine against Alzheimer's and Parkinson's disease: Insight into the role of Nrf-2 and A2AR signaling

M Ikram, TJ Park, T Ali, MO Kim - Antioxidants, 2020 - mdpi.com
This paper reviews the results of studies conducted on the role of caffeine in the
management of different neurological disorders, such as Parkinson's disease (PD) and …

[HTML][HTML] Deciphering the Potential Neuroprotective Effects of Luteolin against Aβ142-Induced Alzheimer's Disease

S Ahmad, MH Jo, M Ikram, A Khan, MO Kim - International Journal of …, 2021 - mdpi.com
The current study was undertaken to unveil the protective effects of Luteolin, a natural
flavonoid, against amyloid-beta (Aβ1–42)-induced neuroinflammation, amyloidogenesis …

[HTML][HTML] Caffeine and its antioxidant properties—it is all about dose and source

BE Ősz, G Jîtcă, RE Ștefănescu, A Pușcaș… - International journal of …, 2022 - mdpi.com
Caffeine is the most frequently used substance with a central nervous system stimulant
effect, but its consumption is most often due to the intake of foods and drinks that contain it …