Aspidosperma species: A review of their chemistry and biological activities

VL de Almeida, CG Silva, AF Silva… - Journal of …, 2019 - Elsevier
Abstract Ethnopharmacological relevance Species of Aspidosperma are known popularly as
“peroba, guatambu, carapanaúba, pau-pereiro” and “quina”. The genus can be found in the …

Concise Total Syntheses of Pyrido[4,3‐b]carbazole Alkaloids Using Copper‐Mediated 6π‐Electrocyclization

T Itoh, T Abe, T Choshi, T Nishiyama… - European Journal of …, 2016 - Wiley Online Library
Abstract Concise syntheses of 9‐methoxyellipticine, 3, 4‐dihydroellipticine (µ‐alkaloid D), 1,
2, 3, 4‐tetrahydroellipticine, 2‐methyl‐1, 2, 3, 4‐tetrahydroellipticine, olivacine, 3, 4 …

Synthesis and cytotoxicity of pyrido [4, 3-b] carbazole alkaloids against HCT-116 and HL-60 cells

T Itoh, N Hatae, T Nishiyama, T Choshi… - Medicinal Chemistry …, 2018 - Springer
Ellipticine, olivacine, and their five reduced natural variants were synthesized via a
palladium-catalyzed tandem cyclization/cross-coupling reaction as the key step. In addition …

The toxicity of Aspidosperma subincanum to MCF7 cells is related to modulation of oxidative status and proinflammatory pathways

AF Santos, NSRS Mota, EM Schiefer… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Cancer is an inflammatory disease because
carcinogenesis and tumor progression depend on intrinsic and extrinsic inflammatory …

クロスカップリング反応を基軸とするインドールアルカロイドの合成

阿部匠, 石倉稔 - 有機合成化学協会誌, 2016 - jstage.jst.go.jp
抄録 In our continuing study of the reactivity and synthetic application of indolylborate as a
versatile synthetic intermediate, we found that the use of indolylborate in palladium …