OBJECTIVE: Large health care utilization databases are frequently used in variety of
settings to study the use and outcomes of therapeutics. Their size allows the study of …

Background. Falls in older people are associated with poor prognosis. Medication use is a
potential cause of falls. Our aim was to systemically review all original articles examining …

Objectives To investigate the association between antidepressant treatment and risk of
several potential adverse outcomes in older people with depression and to examine risks by …

Objective To develop and validate an updated version of the QFracture algorithm for
estimating the risk of a patient sustaining an osteoporotic fracture or hip fracture in a primary …

Objective To develop and validate two new fracture risk algorithms (QFractureScores) for
estimating the individual risk of osteoporotic fracture or hip fracture over 10 years. Design …

The self‐controlled case series method was developed to investigate associations between
acute outcomes and transient exposures, using only data on cases, that is, on individuals …

Neuropathic pain is due to lesion or dysfunction of the peripheral or central nervous system.
Tricyclic antidepressants and anticonvulsants have long been the mainstay of treatment of …

Depression and falls have a significant bidirectional relationship. Excessive fear of falling,
which is frequently associated with depression, also increases the risk of falls. Both …

The available data on bone fractures in hemodialysis (HD) patients are limited to results of a
few studies of subgroups of patients in the United States. This study describes the …

Background Depression and osteoporotic fractures are common ailments among elderly
persons. Selective serotonin reuptake inhibitors (SSRIs) are frequently used in the treatment …