Nanopore techniques offer a low-cost, label-free, and high-throughput platform that could be
used in single-molecule biosensing and in particular DNA sequencing. Since 2010 …

In nanopore analytics, individual molecules pass through a single nanopore giving rise to
detectable temporary blockades in ionic pore current. Reflecting its simplicity, nanopore …

In systems possessing spatial or dynamical symmetry breaking, Brownian motion combined
with unbiased external input signals, deterministic and random alike, can assist directed …

The sequencing of individual DNA strands with nanopores is under investigation as a rapid,
low-cost platform in which bases are identified in order as the DNA strand is transported …

Abstract α-Hemolysin of Staphylococcus aureus is a self-assembling toxin that forms a water-
filled transmembrane channel upon oligomerization in a lipid membrane. Apart from being …

The creation of synthetic devices that mimic functionality of biological systems is a task of
fundamental importance for the future development of bio-and nanotechnology and also an …

Ion channels play a key role in regulating cell behavior and in electrical signaling. In these
settings, polar and charged functional groups, as well as protein response, compensate for …

Biological protein pores and pore-forming peptides can generate a pathway for the flux of
ions and other charged or polar molecules across cellular membranes. In nature, these …

Nanometer-sized pores can be used to detect and characterize biopolymers, such as DNA,
RNA, and polypeptides, with single-molecule resolution. Experiments performed with the 1.5 …

With the continued improvement of sequencing technologies, the prospect of genome-based
medicine is now at the forefront of scientific research. To realize this potential, however, a …