Genetic and epigenetic instability as an underlying driver of progression and aggressive behavior in IDH-mutant astrocytoma
TE Richardson, JM Walker, D Hambardzumyan… - Acta …, 2024 - Springer
In recent years, the classification of adult-type diffuse gliomas has undergone a revolution,
wherein specific molecular features now represent defining diagnostic criteria of IDH-wild …
wherein specific molecular features now represent defining diagnostic criteria of IDH-wild …
Mutational burden and immune recognition of gliomas
Mutational burden and immune recognition of gliomas : Current Opinion in Oncology
Mutational burden and immune recognition of gliomas : Current Opinion in Oncology Log in or …
Mutational burden and immune recognition of gliomas : Current Opinion in Oncology Log in or …
Modeling therapy-driven evolution of glioblastoma with patient-derived xenografts
Simple Summary Glioblastoma (GBM) is the most common and aggressive adult-type
diffusely infiltrating glioma. These tumors invariably develop resistance to standard …
diffusely infiltrating glioma. These tumors invariably develop resistance to standard …
Clinical trials of oncolytic viruses in glioblastoma
ML Shoaf, KB Peters - Advances in Oncology, 2022 - advances-oncology.com
Background Diffuse gliomas are the most common primary central nervous system tumor in
adults and can be classified by histology and molecular alternations into grade 2 to 4 …
adults and can be classified by histology and molecular alternations into grade 2 to 4 …
Pathways to hypermutation in high-grade gliomas: Mechanisms, syndromes, and opportunities for immunotherapy
T Haynes, MR Gilbert, K Breen… - Neuro-Oncology …, 2024 - academic.oup.com
Despite rapid advances in the field of immunotherapy, including the success of immune
checkpoint inhibition in treating multiple cancer types, clinical response in high-grade …
checkpoint inhibition in treating multiple cancer types, clinical response in high-grade …
Gene therapy for the treatment of malignant glioma
DY Zhang, L Singer, AM Sonabend… - Advances in …, 2021 - advances-oncology.com
In the United States, approximately 21,000 new cases of malignant gliomas are diagnosed
per year [1]. Although patients with low-grade glioma generally have good prognosis [2] …
per year [1]. Although patients with low-grade glioma generally have good prognosis [2] …