Spirocyclic derivatives as antioxidants: A review

K Acosta-Quiroga, C Rojas-Pena, LS Nerio… - RSC …, 2021 - pubs.rsc.org
In recent years, spiro compounds have attracted significant interest in medicinal chemistry
due to their numerous biological activities attributed primarily to their versatility and structural …

A brief overview on recent advances in spiro [chromane-2, 4′-piperidine]-4 (3H)-one-functionalized compounds in medicinal chemistry research

NG Ghatpande, JS Jadhav, RV Kaproormath… - Bioorganic & Medicinal …, 2020 - Elsevier
Abstract The spiro [chromane-2, 4′-piperidine]-4 (3H)-one is an important pharmacophore.
It is a structural component in many drugs, drug candidates (or lead compounds) and …

Dimers of coumarin-1, 2, 3-triazole hybrids bearing alkyl spacer: Design, microwave-assisted synthesis, molecular docking and evaluation as antimycobacterial and …

D Ashok, S Gundu, VK Aamate, MG Devulapally… - Journal of Molecular …, 2018 - Elsevier
The present study demonstrated the synthesis of new series of coumarin-1, 2, 3-triazole
hybrids under microwave irradiation method. Several dimers of coumarin based 1, 2, 3 …

Conventional and microwave-assisted synthesis of new indole-tethered benzimidazole-based 1, 2, 3-triazoles and evaluation of their antimycobacterial, antioxidant …

D Ashok, S Gundu, VK Aamate, MG Devulapally - Molecular Diversity, 2018 - Springer
A new series of triheterocycles containing indole–benzimidazole-based 1, 2, 3-triazole
hybrids have been synthesized in good yields via a microwave-assisted click reaction. All …

Microwave-assisted synthesis, antioxidant and antimicrobial evaluation of 2-indolinone-based bis-1, 2, 3-triazole derivatives

D Ashok, S Gundu, VK Aamate, MG Devulapally - Molecular Diversity, 2018 - Springer
A series of 2-indolinone-based bis-1, 2, 3-triazole derivatives have been synthesized in
excellent yields via microwave-assisted, copper-catalyzed azide-alkyne 1, 3-dipolar …

New Synthetic Approaches to Benzo-Fused Spiro Heterocycles

IZ Musabirov, RR Gataullin - Russian Journal of Organic Chemistry, 2022 - Springer
The review describes syntheses of new benzo-fused spiro heterocycles by reactions of
isatins, oxindoles, and indenoquinoxalines with nitroalkenes, chalcones in the presence of …

Microwave-assisted synthesis of new pyrazole derivatives bearing 1, 2, 3-triazole scaffold as potential antimicrobial agents

D Ashok, R Kavitha, S Gundu… - Journal of the Serbian …, 2017 - doiserbia.nb.rs
A new series of (E)-3-(3-(4-substituted phenyl)-1-phenyl-1H-pyrazol-4-yl)-1-(2-hydroxy-4-((1-
aryl-1H-1-2, 3-triazol-4-yl) methoxy) phenyl)-prop-2-en-1-one derivatives was synthesized …

Synthesis of pyrazolylfuro[2,3-f]chromenes and evaluation of their antimicrobial activity

D Ashok, K Rangu, S Gundu, VH Rao - Chemistry of Heterocyclic …, 2016 - Springer
A new series of furochromene-based pyrazole derivatives has been synthesized from their
chalcone precursors upon reaction with 2-bromo-1-(4-bromophenyl) ethanone in the …

Microwave-assisted synthesis and evaluation of indole based benzofuran scaffolds as antimicrobial and antioxidant agents

D Ashok, G Srinivas, AV Kumar, DM Gandhi - Russian Journal of …, 2016 - Springer
A novel series of indole based benzofuran derivatives has been synthesized under
microwave irradiation and conventional conditions. The structures of the compounds were …

Solvent-free microwave-assisted synthesis and biological evaluation of aurones and flavanones based on 2, 2-dimethylchroman-4-one

D Ashok, RS Kumar, DM Gandhi… - Chemistry of Heterocyclic …, 2016 - Springer
A series of novel 8-aryl-2, 2-dimethyl-2, 3, 7, 8-tetrahydropyrano [3, 2-g] chromene-4, 6-
dione and 2-arylidene-7, 7-dimethyl-6, 7-dihydro-2 H-furo [3, 2-g] chromene-3, 5-dione …