Novel EPR-enhanced strategies for targeted drug delivery in pancreatic cancer: An update

V Mohammadzadeh, N Rahiman… - Journal of Drug Delivery …, 2022 - Elsevier
Pancreatic cancer (PCa) is one of the leading causes of morbidity worldwide, and
theranostic approaches are ventured. The vast stroma surrounding PCa cells has been …

Delivery of stem cell secretome for therapeutic applications

F Li, J Zhang, K Yi, H Wang, H Wei… - ACS Applied Bio …, 2022 - ACS Publications
Intensive studies on stem cell therapy reveal that benefits of stem cells attribute to the
paracrine effects. Hence, direct delivery of stem cell secretome to the injured site shows the …

CaZnO-based nanoghosts for the detection of ssDNA, pCRISPR and recombinant SARS-CoV-2 spike antigen and targeted delivery of doxorubicin

N Rabiee, O Akhavan, Y Fatahi, AM Ghadiri, M Kiani… - Chemosphere, 2022 - Elsevier
Overexpression of proteins/antigens and other gene-related sequences in the bodies could
lead to significant mutations and refractory diseases. Detection and identification of assorted …

[HTML][HTML] Extracellular vesicle mimics made from iPS cell-derived mesenchymal stem cells improve the treatment of metastatic prostate cancer

Q Zhao, B Hai, J Kelly, S Wu, F Liu - Stem cell research & therapy, 2021 - Springer
Abstract Background Extracellular vesicles (EVs) and their mimics from mesenchymal stem
cells (MSCs) are promising drug carriers to improve cancer treatment, but their application is …

New insights into the application of nanoghosts as theranostic tools with an emphasis on cardiovascular diseases

M Qindeel, F Sabir, S Sargazi… - Journal of Nanoparticle …, 2021 - Springer
Cardiovascular diseases (CVDs), along with myocardial infarction and inflammatory heart
disease, account for the world's most expansive health concerns. Even though the …

Nano-Ghosts: Biomimetic membranal vesicles, technology and characterization

J Oieni, L Levy, NL Khait, L Yosef, B Schoen, M Fliman… - Methods, 2020 - Elsevier
Currently, nano-carriers for anti-cancer drug delivery are complex systems, which struggle
with immunogenicity and enhanced permeability effect (EPR)-related problems that halt the …

Nano-ghosts: Novel biomimetic nano-vesicles for the delivery of antisense oligonucleotides

J Oieni, A Lolli, D D'Atri, N Kops, A Yayon… - Journal of Controlled …, 2021 - Elsevier
Antisense oligonucleotides (ASOs) carry an enormous therapeutic potential in different
research areas, however, the lack of appropriate carriers for their delivery to the target …

Cell-derived nanovesicles as exosome-mimetics for drug delivery purposes: uses and recommendations

YH Ou, S Zou, WJ Goh, JW Wang, M Wacker… - Bio-Carrier Vectors …, 2021 - Springer
Abstract Cell-derived Drug Delivery Systems (DDSs), particularly exosomes, have grown in
popularity and have been increasingly explored as novel DDSs, due to their intrinsic …

TRAIL Coated Genetically Engineered Immunotherapeutic Nano‐Ghosts Vesicles Target Human Melanoma‐Avoiding the Need for High Effective Therapeutic …

L Levy, T Davidov, KK Kolluri, A Fridman… - Advanced Functional …, 2022 - Wiley Online Library
Cancer cell therapy using cytotoxic T lymphocytes (CTL) or mesenchymal stem cells (MSC)
possesses hurdles due to the cells, susceptibility to host induced changes. Here, versatile …

Adipose Derived Stem Cell‐Conditioned Media As Alternative of Stem Cell Therapy for Diabetic Wound Healing

A Nawaz, S Akram, H Zaman, MS Aslam… - … University Journal of …, 2023 - lgujls.lgu.edu.pk
Diabetes mellitus (DM) is a set of metabolic disorder primarily characterized by chronic
hyperglycaemia state, which is linked with several complications including retinopathy …