Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver and a
leading cause of death in the US and worldwide. HCC remains a global health problem and …

Simple Summary Hepatitis B virus (HBV) infection is the major risk factor for hepatocellular
carcinoma (HCC). Understanding the unique features for HBV-induced HCC can shed new …

Significance: During aging, excessive production of reactive species in the liver leads to
redox imbalance with consequent oxidative damage and impaired organ homeostasis …

As a main producer of complement, the environment in the liver is greatly affected by the
complement system. Although the complement system is considered to have the ability of …

Purpose Liver cancer is one of the most common tumors with the seventh-highest incidence
and the third-highest mortality. Many studies have shown that small extracellular vesicles …

Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related mortality
worldwide. Much recent research has delved into understanding the underlying molecular …

Aging is a necessary process of life associated with various mechanisms, such as genomic
instability, loss of proteostasis, deregulated nutrient sensing, and cellular senescence …

Tumor-associated macrophages (TAMs) are essential components of the immune cell
stroma of hepatocellular carcinoma. TAMs originate from monocytic myeloid-derived …

Liver cancer is the sixth most common cancer and the fourth most fatal cancer in the world.
Immunotherapy has already achieved modest results in the treatment of liver cancer …