The role of Hedgehog signaling pathway in head and neck squamous cell carcinoma

P Cierpikowski, A Leszczyszyn, J Bar - Cells, 2023 - mdpi.com
Head and neck squamous cell carcinoma (HNSCC) is the sixth leading malignancy
worldwide, with a poor prognosis and limited treatment options. Molecularly targeted …

Vibrational imaging techniques for the characterization of hard dental tissues: From bench-top to chair-side

G Orsini, G Orilisi, V Notarstefano, R Monterubbianesi… - Applied Sciences, 2021 - mdpi.com
Currently, various analytical techniques, including scanning electron microscopy, X-Ray
diffraction, microcomputed tomography, and energy dispersive X-ray spectroscopy, are …

Role played by paraoxonase-2 enzyme in cell viability, proliferation and sensitivity to chemotherapy of oral squamous cell carcinoma cell lines

R Campagna, A Belloni, V Pozzi, A Salvucci… - International Journal of …, 2022 - mdpi.com
Oral squamous cell carcinoma represents the most aggressive and frequent form of head
and neck cancer. Due to drug resistance, the 5-year survival rate of patients with advanced …

[HTML][HTML] Uterine leiomyoma as useful model to unveil morphometric and macromolecular collagen state and impairment in fibrotic diseases: An ex-vivo human study

A Belloni, M Furlani, S Greco, V Notarstefano… - … et Biophysica Acta (BBA …, 2022 - Elsevier
Collagen is one of the main components of the extracellular matrix (ECM), involved, among
all, in the maintenance of the structural support of tissues. In fibrotic diseases, collagen is …

Multivariate curve Resolution-Alternating least squares coupled with Raman microspectroscopy: new insights into the kinetic response of primary oral squamous …

V Notarstefano, A Belloni, P Mariani, G Orilisi, G Orsini… - Analyst, 2023 - pubs.rsc.org
Raman MicroSpectroscopy (RMS) is a powerful label-free tool to probe the effects of drugs
at a cellular/subcellular level. It is important, however, to be able to extract relevant …

Preeclampsia correlates with an increase in cannabinoid receptor 1 levels leading to macromolecular alterations in chorionic villi of term placenta

M Lombó, C Giommi, M Paolucci… - International Journal of …, 2022 - mdpi.com
Preeclampsia is a human pregnancy-specific disease characterized by abnormal
placentation that usually presents with maternal hypertension and proteinuria. The main …

Translating Biospectroscopy Techniques to Clinical Settings: A New Paradigm in Point-of-Care Screening and/or Diagnostics

FL Martin - Journal of Personalized Medicine, 2023 - mdpi.com
As healthcare tools increasingly move towards a more digital and computational format,
there is an increasing need for sensor-based technologies that allow for rapid screening …

Antileishmanial potentials of azacitidine and along with meglumine antimoniate on Leishmania major: In silico prediction and in vitro analysis

A Derakhshani, I Sharifi, E Salarkia, A Keyhani… - Plos one, 2023 - journals.plos.org
This study aimed to investigate the in vitro and in silico antileishmanial activity of azacitidine
(AZA) on Leishmania major promastigotes and amastigotes. The in silico method was used …

[HTML][HTML] FTIR Microspectroscopy as a new probe to study human uterine lesions: Characterization of tumor cell lines from uterine smooth muscle cells and evaluation …

A Belloni, V Notarstefano, S Greco, P Pellegrino… - … et Biophysica Acta (BBA …, 2024 - Elsevier
During their life, women are likely to develop uterine diseases, which often compromise their
fertile and perimenopausal age. Besides benign lesions like leiomyomas, several malignant …

A vibrational in vitro approach to evaluate the potential of monoolein nanoparticles as isofuranodiene carrier in MDA-MB 231 breast cancer cell line: New insights from …

V Notarstefano, M Pisani, M Bramucci… - … Acta Part A: Molecular …, 2022 - Elsevier
Isofuranodiene (IFD) is a sesquiterpene occurring in several plant species, which proved to
have multiple anticancer activities. IFD has a lipophilic nature and, hence, a very low water …