Free radicals: properties, sources, targets, and their implication in various diseases

A Phaniendra, DB Jestadi, L Periyasamy - Indian journal of clinical …, 2015 - Springer
Free radicals and other oxidants have gained importance in the field of biology due to their
central role in various physiological conditions as well as their implication in a diverse range …

Carotenoids: potential allies of cardiovascular health?

AG Maria, R Graziano, DO Nicolantonio - Food & nutrition research, 2015 - Taylor & Francis
Carotenoids are a class of natural, fat-soluble pigments found principally in plants. They
have potential antioxidant biological properties because of their chemical structure and …

Free radicals and oxidative stress: signaling mechanisms, redox basis for human diseases, and cell cycle regulation

IZ Sadiq - Current molecular medicine, 2023 - ingentaconnect.com
Free radicals contain one or more unpaired electrons in their valence shell, thus making
them unstable, short-lived, and highly reactive species. Excessive generation of these free …

Dual-phosphorescent iridium (III) complexes extending oxygen sensing from hypoxia to hyperoxia

KY Zhang, P Gao, G Sun, T Zhang, X Li… - Journal of the …, 2018 - ACS Publications
Hypoxia and hyperoxia, referring to states of biological tissues in which oxygen supply is in
sufficient and excessive, respectively, are often pathological conditions. Many luminescent …

Lens regeneration using endogenous stem cells with gain of visual function

H Lin, H Ouyang, J Zhu, S Huang, Z Liu, S Chen… - Nature, 2016 - nature.com
The repair and regeneration of tissues using endogenous stem cells represents an ultimate
goal in regenerative medicine. To our knowledge, human lens regeneration has not yet …

Cataract prevalence and prevention in Europe: a literature review

E Prokofyeva, A Wegener, E Zrenner - Acta ophthalmologica, 2013 - Wiley Online Library
This literature review is aimed at the evaluation of the potential for cataract prevention in
Europe. It was performed using PubMed with Mesh and free‐text terms. Studies included …

Age-related eye disease and gender

M Zetterberg - Maturitas, 2016 - Elsevier
Worldwide, the prevalence of moderate to severe visual impairment and blindness is 285
millions, with 65% of visually impaired and 82% of all blind people being 50 years and older …

[HTML][HTML] Antioxidant defenses in the human eye: A focus on metallothioneins

A Álvarez-Barrios, L Álvarez, M García, E Artime… - Antioxidants, 2021 - mdpi.com
The human eye, the highly specialized organ of vision, is greatly influenced by oxidants of
endogenous and exogenous origin. Oxidative stress affects all structures of the human eye …

[HTML][HTML] Oxidative stress and antioxidants in age-related macular degeneration

N Kushwah, K Bora, M Maurya, MC Pavlovich, J Chen - Antioxidants, 2023 - mdpi.com
Oxidative stress plays a crucial role in aging-related eye diseases, including age-related
macular degeneration (AMD), cataracts, and glaucoma. With age, antioxidant reparative …

Widespread sex dimorphism in aging and age-related diseases

NK Sampathkumar, JI Bravo, Y Chen, PS Danthi… - Human genetics, 2020 - Springer
Although aging is a conserved phenomenon across evolutionary distant species, aspects of
the aging process have been found to differ between males and females of the same …