Forgetting as a form of adaptive engram cell plasticity
TJ Ryan, PW Frankland - Nature Reviews Neuroscience, 2022 - nature.com
One leading hypothesis suggests that memories are stored in ensembles of neurons (or
'engram cells') and that successful recall involves reactivation of these ensembles. A logical …
'engram cells') and that successful recall involves reactivation of these ensembles. A logical …
Locus coeruleus: a new look at the blue spot
The locus coeruleus (LC), or 'blue spot', is a small nucleus located deep in the brainstem
that provides the far-reaching noradrenergic neurotransmitter system of the brain. This …
that provides the far-reaching noradrenergic neurotransmitter system of the brain. This …
Spatiotemporal dynamics of noradrenaline during learned behaviour
Noradrenaline released from the locus coeruleus (LC) is a ubiquitous neuromodulator,,–that
has been linked to multiple functions including arousal,,–, action and sensory gain,–, and …
has been linked to multiple functions including arousal,,–, action and sensory gain,–, and …
A cortico-amygdala neural substrate for endocannabinoid modulation of fear extinction
O Gunduz-Cinar, LI Castillo, M Xia, E Van Leer… - Neuron, 2023 - cell.com
Preclinical and clinical studies implicate endocannabinoids (eCBs) in fear extinction, but the
underlying neural circuit basis of these actions is unclear. Here, we employed in vivo …
underlying neural circuit basis of these actions is unclear. Here, we employed in vivo …
A locus coeruleus-dorsal CA1 dopaminergic circuit modulates memory linking
A Chowdhury, A Luchetti, G Fernandes… - Neuron, 2022 - cell.com
Individual memories are often linked so that the recall of one triggers the recall of another.
For example, contextual memories acquired close in time can be linked, and this is known to …
For example, contextual memories acquired close in time can be linked, and this is known to …
Sex-dependent differences in animal cognition
A Koszałka, K Lustyk, K Pytka - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
The differences in cognitive processes driven by biological sex are the issues that have
gotten growing attention recently. Considering the increasing population suffering from …
gotten growing attention recently. Considering the increasing population suffering from …
Dopamine and fear memory formation in the human amygdala
Learning which environmental cues that predict danger is crucial for survival and
accomplished through Pavlovian fear conditioning. In humans and rodents alike, fear …
accomplished through Pavlovian fear conditioning. In humans and rodents alike, fear …
Associative and plastic thalamic signaling to the lateral amygdala controls fear behavior
B Barsy, K Kocsis, A Magyar, Á Babiczky, M Szabó… - Nature …, 2020 - nature.com
Decades of research support the idea that associations between a conditioned stimulus
(CS) and an unconditioned stimulus (US) are encoded in the lateral amygdala (LA) during …
(CS) and an unconditioned stimulus (US) are encoded in the lateral amygdala (LA) during …
Unrelenting fear under stress: neural circuits and mechanisms for the immediate extinction deficit
S Maren - Frontiers in Systems Neuroscience, 2022 - frontiersin.org
Therapeutic interventions for disorders of fear and anxiety rely on behavioral approaches
that reduce pathological fear memories. For example, learning that threat-predictive stimuli …
that reduce pathological fear memories. For example, learning that threat-predictive stimuli …
The transient response of organic electrochemical transistors
A fast response of organic electrochemical transistors (OECTs) to electrical or chemical
changes is essential for a widespread acceptance of this technology. However, finding …
changes is essential for a widespread acceptance of this technology. However, finding …