Calcific aortic valve disease (CAVD) is a highly prevalent condition that comprises a disease
continuum, ranging from microscopic changes to profound fibro-calcific leaflet remodelling …

The American Society for Apheresis (ASFA) Journal of Clinical Apheresis (JCA) Special
Issue Writing Committee is charged with reviewing, updating, and categorizing indications …

Background: Lipoprotein (a)[Lp (a)] may play a causal role in atherosclerosis. PCSK9
(proprotein convertase subtilisin/kexin 9) inhibitors have been shown to significantly reduce …

The gene encoding PCSK9 was first identified and linked to the phenotype of familial
hypercholesterolaemia approximately 15 years ago. Soon after, studies uncovered the role …

Present review article highlights various cardiovascular risk prediction biomarkers by
incorporating both traditional risk factors to be used as diagnostic markers and recent …

Objectives: This study sought to evaluate the efficacy and safety of subcutaneous
evolocumab compared with oral ezetimibe in hypercholesterolemic patients who are unable …

Aims We performed a network meta-analysis of randomized controlled trials (RCTs) in
patients with primary hypercholesterolaemia to compare the impact of proprotein convertase …

Background: Evolocumab and other anti-PCSK9 antibodies reduced adverse cardiovascular
outcomes in clinical trials of high-risk patients over< 3 years median treatment duration …

Objectives: The purpose of this study was assess the effect of evolocumab (AMG 145) on
lipoprotein (Lp)(a) from a pooled analysis of 4 phase II trials. Background: Lp (a), a low …

Diabetic dyslipidemia is characterized by elevated fasting and postprandial triglycerides, low
HDL-cholesterol, elevated LDL-cholesterol and the predominance of small dense LDL …