While red blood cell (RBC) transfusion is the most common medical intervention in
hospitalized patients, as with any therapeutic, it is not without risk. Allogeneic RBC exposure …

Blood transfusion is the most common procedure completed during a given hospitalization
in the United States. Although often life-saving, transfusions are not risk-free. One sequela …

Blood group alloimmunization is “triggered” when a person lacking a particular antigen is
exposed to this antigen during transfusion or pregnancy. Although exposure to an antigen is …

Background Matching donor red blood cells based on recipient antigens prevents
alloimmunisation. Knowledge about the immunogenicity of red-blood-cell antigens can help …

Autoimmune hemolytic anemia (AIHA) is an acquired hemolytic disorder, mediated by auto-
antibodies, and has a variable clinical course ranging from fully compensated low grade …

BACKGROUND Most incidentally transfused patients receive only ABO‐D–compatible
transfusions and antibodies are formed in up to 8%. The effect of extended (c, C, E, K, Fya …

Red blood cell (RBC) alloimmunization may occur following transfusion or
pregnancy/delivery. Although observational human studies have described the …

BACKGROUND The reason for the difference in susceptibility to red blood cell (RBC)
alloimmunization among patients with sickle cell disease (SCD) is not clearly understood …

Most adverse blood transfusion (BT) events are immune-mediated and in the majority of
severe reactions antibodies can be identified as causal factors. Alloimmunization not only …

Many different factors influence the propensity of transfusion recipients and pregnant women
to form red blood cell alloantibodies (RBCA). RBCA may cause hemolytic transfusion …