A multi-cohort and multi-omics meta-analysis framework to identify network-based gene signatures
Although massive amounts of condition-specific molecular profiles are being accumulated in
public repositories every day, meaningful interpretation of these data remains a major …
public repositories every day, meaningful interpretation of these data remains a major …
GSMA: an approach to identify robust global and test Gene Signatures using Meta-Analysis
Motivation Recent advances in biomedical research have made massive amount of
transcriptomic data available in public repositories from different sources. Due to the …
transcriptomic data available in public repositories from different sources. Due to the …
Signaling pathway impact analysis by incorporating the importance and specificity of genes (SPIA-IS)
Abstract rlying biology of differentially expressed genes and proteins. Although various
approaches have been proposed to identify cancer-related pathways, most of them only …
approaches have been proposed to identify cancer-related pathways, most of them only …
GeneSurrounder: network-based identification of disease genes in expression data
Background A key challenge of identifying disease–associated genes is analyzing
transcriptomic data in the context of regulatory networks that control cellular processes in …
transcriptomic data in the context of regulatory networks that control cellular processes in …
Statistical Methods for the Network-Based Analysis of Genomic Data
SD Shah - 2019 - search.proquest.com
The focus of this thesis is on evaluating, designing, and applying statistical methods that
elucidate molecular mechanisms by seeking to understand the pathways that contribute to …
elucidate molecular mechanisms by seeking to understand the pathways that contribute to …
Network-based identification of disease genes in expression data: the GeneSurrounder method
The advent of high--throughput transcription profiling technologies has enabled
identification of genes and pathways associated with disease, providing new avenues for …
identification of genes and pathways associated with disease, providing new avenues for …