Catalytic Aerobic Oxidation of C(sp3)−H Bonds
H Sterckx, B Morel, BUW Maes - … Chemie International Edition, 2019 - Wiley Online Library
Oxidation reactions are a key technology to transform hydrocarbons from petroleum
feedstock into chemicals of a higher oxidation state, allowing further chemical …
feedstock into chemicals of a higher oxidation state, allowing further chemical …
[HTML][HTML] Late-stage modification of bioactive compounds: Improving druggability through efficient molecular editing
T Huo, X Zhao, Z Cheng, J Wei, M Zhu, X Dou… - … Pharmaceutica Sinica B, 2024 - Elsevier
Synthetic chemistry plays an indispensable role in drug discovery, contributing to hit
compounds identification, lead compounds optimization, candidate drugs preparation, and …
compounds identification, lead compounds optimization, candidate drugs preparation, and …
Selective Aerobic Oxidation of Methylarenes to Benzaldehydes Catalyzed by N‐Hydroxyphthalimide and Cobalt(II) Acetate in Hexafluoropropan‐2‐ol
Efficient and highly selective catalytic conditions for the aerobic autoxidation of
methylarenes to benzaldehydes, based on N‐hydroxyphthalimide (NHPI) and cobalt (II) …
methylarenes to benzaldehydes, based on N‐hydroxyphthalimide (NHPI) and cobalt (II) …
Co/NHPI-mediated aerobic oxygenation of benzylic C–H bonds in pharmaceutically relevant molecules
DP Hruszkewycz, KC Miles, OR Thiel, SS Stahl - Chemical science, 2017 - pubs.rsc.org
A simple cobalt (II)/N-hydroxyphthalimide catalyst system has been identified for selective
conversion of benzylic methylene groups in pharmaceutically relevant (hetero) arenes to the …
conversion of benzylic methylene groups in pharmaceutically relevant (hetero) arenes to the …
A gC 3 N 4-based heterogeneous photocatalyst for visible light mediated aerobic benzylic C–H oxygenations
P Geng, Y Tang, G Pan, W Wang, J Hu, Y Cai - Green Chemistry, 2019 - pubs.rsc.org
A metal-free heterogeneous photocatalytic system has been developed for highly efficient
benzylic C–H oxygenations using oxygen as an oxidant. This visible light mediated …
benzylic C–H oxygenations using oxygen as an oxidant. This visible light mediated …
Electrochemical benzylic oxidation of C–H bonds
Oxidized products have become increasingly valuable as building blocks for a wide variety
of different processes and fine chemistry, especially in the benzylic position. We report …
of different processes and fine chemistry, especially in the benzylic position. We report …
Regioselective synthesis of 4-functionalized pyridines
C Li, Z Yan, B Wang, J Li, W Lyu, Z Wang, N Jiao… - Chem, 2024 - cell.com
Functionalized pyridines are privileged scaffolds in various fields. The C-4 selective
functionalization of pyridines is perhaps the most convenient protocol to pyridine derivatives …
functionalization of pyridines is perhaps the most convenient protocol to pyridine derivatives …
Recent trends in catalytic sp 3 C–H functionalization of heterocycles
M Kaur, JF Van Humbeck - Organic & Biomolecular Chemistry, 2020 - pubs.rsc.org
Heterocycles are a ubiquitous substructure in organic small molecules designed for use in
materials and medicines. Recent work in catalysis has focused on enabling access to new …
materials and medicines. Recent work in catalysis has focused on enabling access to new …
Visible‐Light‐Induced Oxidation of Diazenyl‐Protected Tetrahydroisoquinolines and Isoindolines for the Synthesis of Functionalized Lactams
A visible‐light‐induced oxidation of diazenyl‐protected tetrahydroisoquinolines and
isoindolines for the synthesis of structurally diverse lactams is developed. The reaction was …
isoindolines for the synthesis of structurally diverse lactams is developed. The reaction was …
The effect of dissolved oxygen on kinetics during continuous biocatalytic oxidations
RM Lindeque, JM Woodley - Organic Process Research & …, 2020 - ACS Publications
Conventional oxidation catalysts frequently exhibit limited selectivity, restricting their use in
industrial syntheses. In particular, for the continuous synthesis of complex active …
industrial syntheses. In particular, for the continuous synthesis of complex active …