Comparative efficacy of racemic ketamine and esketamine for depression: a systematic review and meta-analysis
Background Ketamine appears to have a therapeutic role in certain mental disorders, most
notably depression. However, the comparative performance of different formulations of …
notably depression. However, the comparative performance of different formulations of …
Management of treatment-resistant depression: challenges and strategies
D Voineskos, ZJ Daskalakis… - … disease and treatment, 2020 - Taylor & Francis
Abstract Treatment-resistant depression (TRD) is a subset of Major Depressive Disorder
which does not respond to traditional and first-line therapeutic options. There are several …
which does not respond to traditional and first-line therapeutic options. There are several …
Real-world effectiveness of ketamine in treatment-resistant depression: A systematic review & meta-analysis
Ketamine is a promising therapeutic option in treatment-resistant depression (TRD). The
acute efficacy of ketamine in TRD has been demonstrated in replicated randomised …
acute efficacy of ketamine in TRD has been demonstrated in replicated randomised …
Psychedelics in psychiatry: neuroplastic, immunomodulatory, and neurotransmitter mechanisms
Mounting evidence suggests safety and efficacy of psychedelic compounds as potential
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …
novel therapeutics in psychiatry. Ketamine has been approved by the Food and Drug …
Side-effects associated with ketamine use in depression: a systematic review
B Short, J Fong, V Galvez, W Shelker… - The Lancet Psychiatry, 2018 - thelancet.com
This is the first systematic review of the safety of ketamine in the treatment of depression
after single and repeated doses. We searched MEDLINE, PubMed, PsycINFO, and …
after single and repeated doses. We searched MEDLINE, PubMed, PsycINFO, and …
Comorbid anxiety and depression: clinical and conceptual consideration and transdiagnostic treatment
KW Choi, YK Kim, HJ Jeon - Anxiety disorders: Rethinking and …, 2020 - Springer
Although anxiety and depression have been considered as two distinct entities according to
the diagnostic criteria, anxious depression (comorbid anxiety and depression) is relatively a …
the diagnostic criteria, anxious depression (comorbid anxiety and depression) is relatively a …
[HTML][HTML] Ketamine treatment for depression: a review
This manuscript reviews the clinical evidence regarding single-dose intravenous (IV)
administration of the novel glutamatergic modulator racemic (R, S)-ketamine (hereafter …
administration of the novel glutamatergic modulator racemic (R, S)-ketamine (hereafter …
[HTML][HTML] Novel pharmacological targets in drug development for the treatment of anxiety and anxiety-related disorders
SB Sartori, N Singewald - Pharmacology & therapeutics, 2019 - Elsevier
Current medication for anxiety disorders is suboptimal in terms of efficiency and tolerability,
highlighting the need for improved drug treatments. In this review an overview of drugs …
highlighting the need for improved drug treatments. In this review an overview of drugs …
Improvement in suicidal ideation after ketamine infusion: relationship to reductions in depression and anxiety
Objective Suicide is a psychiatric emergency. Currently, there are no approved
pharmacologic treatments for suicidal ideation. Ketamine is an N-methyl-D-aspartate …
pharmacologic treatments for suicidal ideation. Ketamine is an N-methyl-D-aspartate …
Repeat-dose ketamine augmentation for treatment-resistant depression with chronic suicidal ideation: a randomized, double blind, placebo controlled trial
DF Ionescu, KH Bentley, M Eikermann, N Taylor… - Journal of affective …, 2019 - Elsevier
Background Several studies indicate that ketamine has rapid antidepressant effects in
patients with treatment-resistant depression (TRD). The extent to which repeated doses of …
patients with treatment-resistant depression (TRD). The extent to which repeated doses of …