Autosomal dominant cerebellar ataxias (ADCAs) are a group of neurodegenerative
disorders characterized by degeneration of the cerebellum and its connections. All ADCAs …

Stroke is the second most common cause of death and is a major cause of permanent
disability. Given the current demographic trend of an ageing population and associated …

Alzheimer's disease (AD) is the most common type of dementia in the elderly population.
The disease is characterized by progressive memory loss, cerebral atrophy, extensive …

The plasma membrane remains a major barrier for intracellular drug delivery, to overcome
this issue, a variety of approaches have been developed and used to deliver therapeutic …

Huntington's disease (HD) arises from the abnormal expansion of CAG repeats in the
huntingtin gene (HTT), resulting in the production of the mutant huntingtin protein (mHTT) …

Background Naringenin is a powerful antioxidant and anti-inflammatory flavonoid which has
been widely used as a therapeutic agent in various toxic models. However, few studies have …

Huntington's disease (HD) is a genetic neurodegenerative disorder characterized by
neuronal loss and motor dysfunction. Although there is no effective treatment, stem cell …

Stem cells (SCs) are clonogenic cells that develop into the specialized cells which later
responsible for making up various types of tissue in the human body. SCs are not only the …

Background Peripheral biomarkers for major psychiatric disorders have been an elusive
target for the last half a century. Dermal fibroblasts are a simple, relevant, and much …

Since their discovery in 2006, induced pluripotent stem cells (iPSCs) have opened up a
world of possibilities for regenerative medicine and novel cell-based therapeutics. Now, over …